| Reaction Details |
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 | Report a problem with these data |
| Target | Protease |
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| Ligand | BDBM50163750 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1822317 (CHEMBL4322081) |
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| Ki | 13±n/a nM |
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| Citation |  Wu, G; Zhao, T; Kang, D; Zhang, J; Song, Y; Namasivayam, V; Kongsted, J; Pannecouque, C; De Clercq, E; Poongavanam, V; Liu, X; Zhan, P Overview of Recent Strategic Advances in Medicinal Chemistry. J Med Chem62:9375-9414 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protease |
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| Name: | Protease |
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| Synonyms: | n/a |
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| Type: | Enzyme |
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| Mol. Mass.: | 10904.79 |
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| Organism: | Human immunodeficiency virus 1 (HIV-1) |
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| Description: | Q9YQ12 |
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| Residue: | 99 |
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| Sequence: | PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50163750 |
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| n/a |
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| Name | BDBM50163750 |
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| Synonyms: | CHEMBL3797292 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H46N6O7S |
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| Mol. Mass. | 706.851 |
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| SMILES | COc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@@H](O)[C@H](Cc1ccccc1)n1cc(CNC(=O)c2ccc(CNC(=O)OC(C)(C)C)cc2)nn1 |r| |
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| Structure | 
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