Reaction Details |
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Target | Somatostatin receptor type 1 |
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Ligand | BDBM50064029 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_200358 (CHEMBL807425) |
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Ki | 6800±n/a nM |
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Citation | Hirschmann, R; Hynes, J; Cichy-Knight, MA; van Rijn, RD; Sprengeler, PA; Spoors, PG; Shakespeare, WC; Pietranico-Cole, S; Barbosa, J; Liu, J; Yao, W; Rohrer, S; Smith, AB Modulation of receptor and receptor subtype affinities using diastereomeric and enantiomeric monosaccharide scaffolds as a means to structural and biological diversity. A new route to ether synthesis. J Med Chem41:1382-91 (1998) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Somatostatin receptor type 1 |
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Name: | Somatostatin receptor type 1 |
Synonyms: | SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1) |
Type: | Enzyme |
Mol. Mass.: | 42692.81 |
Organism: | Homo sapiens (Human) |
Description: | P30872 |
Residue: | 391 |
Sequence: | MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAIL
ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL
RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG
VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC
LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQD
DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKS
RAYSVEDFQPENLESGGVFRNGTCTSRITTL
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BDBM50064029 |
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n/a |
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Name | BDBM50064029 |
Synonyms: | 5-{(2R,3S,5R,6R)-3-Benzyloxy-5-(1H-imidazol-4-ylmethoxy)-6-[2-(1H-indol-3-yl)-ethoxy]-tetrahydro-pyran-2-ylmethoxy}-pentylamine | CHEMBL28824 |
Type | Small organic molecule |
Emp. Form. | C32H42N4O5 |
Mol. Mass. | 562.6997 |
SMILES | NCCCCCOC[C@H]1O[C@@H](OCCc2c[nH]c3ccccc23)[C@@H](C[C@@H]1OCc1ccccc1)OCc1cnc[nH]1 |
Structure |
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