| Reaction Details |
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 | Report a problem with these data |
| Target | Chromodomain Y-like protein |
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| Ligand | BDBM50515906 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1862774 (CHEMBL4363630) |
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| Kd | 19400±n/a nM |
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| Citation |  Yang, L; Liu, Y; Fan, M; Zhu, G; Jin, H; Liang, J; Liu, Z; Huang, Z; Zhang, L Identification and characterization of benzo[d]oxazol-2(3H)-one derivatives as the first potent and selective small-molecule inhibitors of chromodomain protein CDYL. Eur J Med Chem182:0 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chromodomain Y-like protein |
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| Name: | Chromodomain Y-like protein |
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| Synonyms: | 4.2.1.- | CDY-like | CDYL | CDYL1 | CDYL_HUMAN | Chromodomain Y-like protein | Crotonyl-CoA hydratase | Synonyms=CDYL1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66506.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_116952 |
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| Residue: | 598 |
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| Sequence: | MTFQASHRSAWGKSRKKNWQYEGPTQKLFLKRNNVSAPDGPSDPSISVSSEQSGAQQPPA
LQVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHTEKQKES
TLTRTNRTSPNNARKQISRSTNSNFSKTSPKALVIGKDHESKNSQLFAASQKFRKNTAPS
LSSRKNMDLAKSGIKILVPKSPVKSRTAVDGFQSESPEKLDPVEQGQEDTVAPEVAAEKP
VGALLGPGAERARMGSRPRIHPLVPQVPGPVTAAMATGLAVNGKGTSPFMDALTANGTTN
IQTSVTGVTASKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTK
SSENNSLNPEVMREVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRES
TKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQ
SPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKEL
ASCNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGMDSMLKYLQRKIDEF
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| BDBM50515906 |
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| n/a |
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| Name | BDBM50515906 |
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| Synonyms: | CHEMBL4538036 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H17NO3 |
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| Mol. Mass. | 331.3646 |
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| SMILES | CN1C(=O)C(O)(CC(=O)c2ccc3ccccc3c2)c2ccccc12 |
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| Structure | 
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