| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 15 member 1 |
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| Ligand | BDBM50519221 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1874436 (CHEMBL4375725) |
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| Ki | 2500000±n/a nM |
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| Citation |  Jiang, Q; Zhang, J; Tong, P; Gao, Y; Lv, Y; Wang, C; Luo, M; Sun, M; Wang, J; Feng, Y; Cao, L; Wang, G; Wang, Y; Kan, Q; Zhang, T; Wang, Y; Liu, K; Sun, J; He, Z Bioactivatable Pseudotripeptidization of Cyclic Dipeptides To Increase the Affinity toward Oligopeptide Transporter 1 for Enhanced Oral Absorption: An Application to Cyclo(l-Hyp-l-Ser) (JBP485). J Med Chem62:7708-7721 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 15 member 1 |
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| Name: | Solute carrier family 15 member 1 |
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| Synonyms: | Intestinal H(+)/peptide cotransporter | Oligopeptide transporter small intestine isoform | Oligopeptide transporter, small intestine isoform | PEPT1 | Peptide transporter 1 | S15A1_HUMAN | SLC15A1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78818.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1488839 |
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| Residue: | 708 |
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| Sequence: | MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFV
ALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPV
HVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTII
TPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCI
GFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQ
GSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKK
MAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGP
MSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQK
PEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQ
PNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSV
TGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVC
VIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM
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| BDBM50519221 |
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| n/a |
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| Name | BDBM50519221 |
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| Synonyms: | CHEMBL4460144 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H14N2O5 |
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| Mol. Mass. | 218.2072 |
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| SMILES | OC[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1)C(O)=O |r| |
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| Structure | 
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