Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Cannabinoid receptor 1 | ||
Ligand | BDBM50074315 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_46641 (CHEMBL658897) | ||
Ki | 346±n/a nM | ||
Citation | Lan, R; Liu, Q; Fan, P; Lin, S; Fernando, SR; McCallion, D; Pertwee, R; Makriyannis, A Structure-activity relationships of pyrazole derivatives as cannabinoid receptor antagonists. J Med Chem42:769-76 (1999) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Cannabinoid receptor 1 | |||
Name: | Cannabinoid receptor 1 | ||
Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 52856.55 | ||
Organism: | Rattus norvegicus (rat) | ||
Description: | P20272 | ||
Residue: | 473 | ||
Sequence: |
| ||
BDBM50074315 | |||
n/a | |||
Name | BDBM50074315 | ||
Synonyms: | 5-(2-Amino-phenyl)-1-(2,4-dichloro-phenyl)-4-methyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide | CHEMBL424527 | ||
Type | Small organic molecule | ||
Emp. Form. | C22H23Cl2N5O | ||
Mol. Mass. | 444.357 | ||
SMILES | Cc1c(nn(c1-c1ccccc1N)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 |(2.9,-5.18,;3.85,-6.4,;5.39,-6.33,;5.92,-7.78,;4.7,-8.74,;3.41,-7.87,;1.97,-8.41,;1.73,-9.93,;.29,-10.44,;-.9,-9.47,;-.64,-7.94,;.8,-7.42,;.78,-5.88,;4.76,-10.28,;3.47,-11.08,;3.51,-12.62,;4.88,-13.35,;4.92,-14.89,;6.17,-12.53,;6.11,-10.99,;7.42,-10.17,;6.24,-5.05,;5.56,-3.67,;7.78,-5.17,;8.64,-3.88,;7.96,-2.51,;8.83,-1.23,;10.37,-1.33,;11.02,-2.73,;10.17,-3.99,)| | ||
Structure |