| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50074318 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_47004 (CHEMBL657998) |
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| Ki | 1260±n/a nM |
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| Citation |  Lan, R; Liu, Q; Fan, P; Lin, S; Fernando, SR; McCallion, D; Pertwee, R; Makriyannis, A Structure-activity relationships of pyrazole derivatives as cannabinoid receptor antagonists. J Med Chem42:769-76 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38220.43 |
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| Organism: | MOUSE |
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| Description: | P47936 |
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| Residue: | 347 |
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| Sequence: | MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILS
SRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLD
VRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYA
LRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
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| BDBM50074318 |
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| n/a |
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| Name | BDBM50074318 |
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| Synonyms: | 5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methyl-1H-pyrazole-3-carboxylic acid cyclohexyl-methyl-amide | CHEMBL285473 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24BrCl2N3O |
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| Mol. Mass. | 521.277 |
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| SMILES | CN(C1CCCCC1)C(=O)c1nn(c(c1C)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl |
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| Structure | 
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