| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 2 |
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| Ligand | BDBM50526793 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1901118 (CHEMBL4403340) |
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| IC50 | 6.4±n/a nM |
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| Citation |  Teng, Y; Lu, K; Zhang, Q; Zhao, L; Huang, Y; Ingarra, AM; Galons, H; Li, T; Cui, S; Yu, P; Oumata, N Recent advances in the development of cyclin-dependent kinase 7 inhibitors. Eur J Med Chem183:0 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 2 |
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| Name: | Cyclin-dependent kinase 2 |
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| Synonyms: | CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 33938.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24941 |
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| Residue: | 298 |
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| Sequence: | MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
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| BDBM50526793 |
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| n/a |
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| Name | BDBM50526793 |
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| Synonyms: | CHEMBL4562323 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H28N8O |
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| Mol. Mass. | 432.5214 |
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| SMILES | CC(C)c1cnn2c(NCc3ccccc3-n3cccn3)nc(OC3CCCNC3)nc12 |
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| Structure | 
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