| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cyclin-dependent kinase 7 |
|---|
| Ligand | BDBM50526801 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1901130 (CHEMBL4403352) |
|---|
| IC50 | <20±n/a nM |
|---|
| Citation |  Teng, Y; Lu, K; Zhang, Q; Zhao, L; Huang, Y; Ingarra, AM; Galons, H; Li, T; Cui, S; Yu, P; Oumata, N Recent advances in the development of cyclin-dependent kinase 7 inhibitors. Eur J Med Chem183:0 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cyclin-dependent kinase 7 |
|---|
| Name: | Cyclin-dependent kinase 7 |
|---|
| Synonyms: | 39 kDa protein kinase | CAK | CAK1 | CDK-activating kinase | CDK-activating kinase 1 (CAK) | CDK7 | CDK7_HUMAN | CDKN7 | Cell division protein kinase 7 | Cyclin-Dependent Kinase 7 (CDK7) | Cyclin-dependent kinase 7 (CDK7/cyclin H) | MO15 | P39 Mo15 | STK1 | TFIIH basal transcription factor complex kinase subunit |
|---|
| Type: | Enzyme Subunit |
|---|
| Mol. Mass.: | 39047.01 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 346 |
|---|
| Sequence: | MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL
REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM
TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRA
PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM
CSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPG
PTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF
|
|
|
|---|
| BDBM50526801 |
|---|
| n/a |
|---|
| Name | BDBM50526801 |
|---|
| Synonyms: | CHEMBL4474655 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H17F3N6 |
|---|
| Mol. Mass. | 362.3523 |
|---|
| SMILES | FC(F)(F)c1cnc(N[C@H]2CCCNC2)nc1-c1n[nH]c2ccccc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
