| Reaction Details |
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 | Report a problem with these data |
| Target | Midkine |
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| Ligand | BDBM50529728 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1909742 (CHEMBL4412188) |
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| Kd | 52±n/a nM |
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| Citation |  Yao, W; Chen, M; Dou, X; Jin, H; Zhang, X; Zhu, Y; Sha, M; Liu, Z; Meng, X; Zhang, L; Zhu, S; Li, Z Unravel a neuroactive sHA sulfation pattern with neurogenesis activity by a library of defined oligosaccharides. Eur J Med Chem163:583-596 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Midkine |
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| Name: | Midkine |
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| Synonyms: | ARAP | Amphiregulin-associated protein | MDK | MK | MK1 | MK_HUMAN | Midgestation and kidney protein | NEGF2 | Neurite outgrowth-promoting factor 2 | Neurite outgrowth-promoting protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 15605.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_805023 |
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| Residue: | 143 |
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| Sequence: | MQHRGFLLLTLLALLALTSAVAKKKDKVKKGGPGSECAEWAWGPCTPSSKDCGVGFREGT
CGAQTQRIRCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQGTLKKARYNAQCQETI
RVTKPCTPKTKAKAKAKKGKGKD
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| BDBM50529728 |
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| n/a |
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| Name | BDBM50529728 |
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| Synonyms: | CHEMBL4540967 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H55N5O29S2 |
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| Mol. Mass. | 1061.947 |
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| SMILES | [H][C@]1(O[C@@H]2O[C@H](C(O)=O)[C@@]([H])(O[C@@H]3O[C@H](COS(O)(=O)=O)[C@@H](O)[C@]([H])(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)[C@H]3NC(C)=O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H](OCCCCCCN=[N+]=[N-])[C@@H]1NC(C)=O |r| |
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| Structure | 
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