| Reaction Details |
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 | Report a problem with these data |
| Target | Peptide deformylase |
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| Ligand | BDBM50535516 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1930889 (CHEMBL4434140) |
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| Ki | 60±n/a nM |
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| Citation |  Spletstoser, JT; Dreabit, J; Knox, AN; Benowitz, A; Campobasso, N; Ward, P; Cui, G; Lewandowski, T; McCloskey, L; Aubart, KM Discovery of piperazic acid peptide deformylase inhibitors with in vivo activity for respiratory tract and skin infections. Bioorg Med Chem Lett29:2410-2414 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptide deformylase |
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| Name: | Peptide deformylase |
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| Synonyms: | 3.5.1.88 | BON69_24600 | BON94_18585 | D9G11_24945 | D9G11_25760 | D9J60_20755 | FORC82_p394 | PDF | Polypeptide deformylase | SAMEA3472033_04733 | def | def_2 |
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| Type: | n/a |
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| Mol. Mass.: | 16901.39 |
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| Organism: | Escherichia coli |
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| Description: | n/a |
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| Residue: | 150 |
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| Sequence: | MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEKGIGLAATQVDIHQRIIV
IDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFE
LEADGLLAICIGLRLGNGKYCTLRLFFNQV
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| BDBM50535516 |
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| n/a |
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| Name | BDBM50535516 |
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| Synonyms: | CHEMBL4542964 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H35N3O5 |
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| Mol. Mass. | 397.509 |
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| SMILES | CCC(=O)[C@@H](NC(=O)[C@@H]1CCCNN1C(=O)[C@H](CC(C)C)CC(O)=O)C(C)C |r| |
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| Structure | 
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