| Reaction Details |
|---|
 | Report a problem with these data |
| Target | B2 bradykinin receptor |
|---|
| Ligand | BDBM50093770 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_40297 |
|---|
| Kd | 7400±n/a nM |
|---|
| Citation |  Artis, DR; Brotherton-Pleiss, C; Pease, JH; Lin, CJ; Ferla, SW; Newman, SR; Bhakta, S; Ostrelich, H; Jarnagin, K Structure-based design of six novel classes of nonpeptide antagonists of the bradykinin B2 receptor. Bioorg Med Chem Lett10:2421-5 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| B2 bradykinin receptor |
|---|
| Name: | B2 bradykinin receptor |
|---|
| Synonyms: | B2 BRADYKININ | B2 bradykinin receptor | B2R | BDKRB2 | BK-2 receptor | BKR2 | BKRB2_HUMAN | Bradykinin B2 receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44467.17 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | B2 BRADYKININ BDKRB2 HUMAN::P30411 |
|---|
| Residue: | 391 |
|---|
| Sequence: | MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ
PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN
FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV
IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVI
TFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGI
LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEP
IQMENSMGTLRTSISVERQIHKLQDWAGSRQ
|
|
|
|---|
| BDBM50093770 |
|---|
| n/a |
|---|
| Name | BDBM50093770 |
|---|
| Synonyms: | 4-Aminomethyl-N-[(S)-1-(4-butyl-pyridin-2-yl)-2-cyclohexyl-ethyl]-benzamide | CHEMBL311593 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H35N3O |
|---|
| Mol. Mass. | 393.5649 |
|---|
| SMILES | CCCCc1ccnc(c1)[C@H](CC1CCCCC1)NC(=O)c1ccc(CN)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
