| Reaction Details |
|---|
 | Report a problem with these data |
| Target | B2 bradykinin receptor |
|---|
| Ligand | BDBM50093772 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_40297 |
|---|
| Kd | 12000±n/a nM |
|---|
| Citation |  Artis, DR; Brotherton-Pleiss, C; Pease, JH; Lin, CJ; Ferla, SW; Newman, SR; Bhakta, S; Ostrelich, H; Jarnagin, K Structure-based design of six novel classes of nonpeptide antagonists of the bradykinin B2 receptor. Bioorg Med Chem Lett10:2421-5 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| B2 bradykinin receptor |
|---|
| Name: | B2 bradykinin receptor |
|---|
| Synonyms: | B2 BRADYKININ | B2 bradykinin receptor | B2R | BDKRB2 | BK-2 receptor | BKR2 | BKRB2_HUMAN | Bradykinin B2 receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44467.17 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | B2 BRADYKININ BDKRB2 HUMAN::P30411 |
|---|
| Residue: | 391 |
|---|
| Sequence: | MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ
PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN
FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV
IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVI
TFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGI
LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEP
IQMENSMGTLRTSISVERQIHKLQDWAGSRQ
|
|
|
|---|
| BDBM50093772 |
|---|
| n/a |
|---|
| Name | BDBM50093772 |
|---|
| Synonyms: | CHEMBL311191 | N-[3-(7-Dibenzylamino-3-guanidinomethyl-2-oxo-5-phenyl-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)-propyl]-guanidine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C35H39N9O |
|---|
| Mol. Mass. | 601.7439 |
|---|
| SMILES | [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-1-[#7]=[#6](-c2ccccc2)-c2cc(ccc2-[#7](-[#6]-[#6]-[#6]-[#7]-[#6](-[#7])=[#7])-[#6]-1=O)-[#7](-[#6]-c1ccccc1)-[#6]-c1ccccc1 |t:6| |
|---|
| Structure | 
|
|---|
Search and Browse
