| Reaction Details |
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 | Report a problem with these data |
| Target | Procathepsin L |
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| Ligand | BDBM50095490 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48368 (CHEMBL661684) |
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| IC50 | 150±n/a nM |
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| Citation |  Falgueyret, JP; Oballa, RM; Okamoto, O; Wesolowski, G; Aubin, Y; Rydzewski, RM; Prasit, P; Riendeau, D; Rodan, SB; Percival, MD Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L. J Med Chem44:94-104 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Procathepsin L |
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| Name: | Procathepsin L |
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| Synonyms: | CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein |
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| Type: | Enzyme |
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| Mol. Mass.: | 37557.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purchased from Calbiochem (San Diego, CA). |
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| Residue: | 333 |
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| Sequence: | MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
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| BDBM50095490 |
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| n/a |
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| Name | BDBM50095490 |
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| Synonyms: | 3-Benzyloxymethyl-pyrrolidine-1-carbonitrile | CHEMBL274616 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16N2O |
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| Mol. Mass. | 216.2789 |
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| SMILES | N#CN1CCC(COCc2ccccc2)C1 |
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| Structure | 
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