| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Proline--tRNA ligase, cytoplasmic |
|---|
| Ligand | BDBM50097098 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_223470 |
|---|
| IC50 | 32000±n/a nM |
|---|
| Citation |  Yu, XY; Hill, JM; Yu, G; Yang, Y; Kluge, AF; Keith, D; Finn, J; Gallant, P; Silverman, J; Lim, A A series of quinoline analogues as potent inhibitors of C. albicans prolyl tRNA synthetase. Bioorg Med Chem Lett11:541-4 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Proline--tRNA ligase, cytoplasmic |
|---|
| Name: | Proline--tRNA ligase, cytoplasmic |
|---|
| Synonyms: | PRS | ProRS | Proline--tRNA ligase | Prolyl-tRNA synthetase | Prolyl-tRNA synthetase, cytoplasmic | SYPC_CANAX |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 66202.25 |
|---|
| Organism: | Candida albicans |
|---|
| Description: | ChEMBL_223470 |
|---|
| Residue: | 575 |
|---|
| Sequence: | MIIIKRFLHIKTVPKSYGNQLSKFKYSKQIPTHEVLTKLGYITYPRAGLVNWSKMGLLIQ
NKISQIIRQRMDEIQFEEVSLSLISHKELWKLTNRWDQEEIFKLVGDEYLLVPTAEEEIT
NYVKKQFLESYKNFPLALYQINPKFRNEKRPRGGLLRGKEFLMKDAYSFDLNESEAMKTY
EKVVGAYHKIFQDLGIPYVKAEADSGDIGGSLSHEWHYLNSSGEDTVFECNECHNVSNME
KALSYPKEIDETIEVSVIYFTTEDKSTLICAYYPSNRVLEPKFIQNEIPDIDLDSINDLS
EFNHDISTRIVRIMDSRLSSRSKFPDFPISNFINRSLITTLTDIPIVLAQEGEICGHCEE
GKLSASSAIEVGHTFYLGDKYSKPLDLEVDVPTSNNSIEKQRIMMGCYGIGISRIIAAIA
EINRDEKGLKWPRSIAPWEVTVVEVSKQKQLKNVNDNNHHNNPQDNFQEIYNILNQANID
YRLDNRSDSMGKKLKQSDLLGIPLSIILGNQYPIIEIEVRGNKKNNNNNSWLQSYTENKD
QFDWKVETDAQGNDTKHYIHKDGLVTVVNSLLNDM
|
|
|
|---|
| BDBM50097098 |
|---|
| n/a |
|---|
| Name | BDBM50097098 |
|---|
| Synonyms: | 2-(5-Chloro-thiophen-2-yl)-quinoline-4-carboxylic acid | CHEMBL153072 | cid_625773 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H8ClNO2S |
|---|
| Mol. Mass. | 289.737 |
|---|
| SMILES | OC(=O)c1cc(nc2ccccc12)-c1ccc(Cl)s1 |
|---|
| Structure | 
|
|---|
Search and Browse
