Ki Summary

Reaction Details

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Target

Beta-2 adrenergic receptor

Ligand

BDBM50002134

Substrate/Competitor

n/a

Meas. Tech.

ChEBML_216183

EC50

262000±n/a nM

Citation

Hu, B; Ellingboe, J; Gunawan, I; Han, S; Largis, E; Li, Z; Malamas, M; Mulvey, R; Oliphant, A; Sum, FW; Tillett, J; Wong, V 2,4-Thiazolidinediones as potent and selective human beta3 agonists. Bioorg Med Chem Lett11:757-60 (2001) [PubMed]

More Info.:

Get all data from this article, Assay Method

Beta-2 adrenergic receptor

Name:

Beta-2 adrenergic receptor

Synonyms:

Type:

n/a

Mol. Mass.:

46461.69

Organism:

Homo sapiens (Human)

Description:

P07550

Residue:

413

Sequence:

MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL

BDBM50002134

n/a

Name

BDBM50002134

Synonyms:

5-((2R)-2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}propyl)-1,3-benzodioxole-2,2-dicarboxylate | 5-{2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-benzo[1,3]dioxole-2,2-dicarboxylate anion; disodium | 5-{2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-benzo[1,3]dioxole-2,2-dicarboxylic acid;Disodium salt | CHEMBL32590 | CL-316243 | Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate | disodium 5-((2R)-2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}propyl)-1,3-benzodioxole-2,2-dicarboxylate | disodium 5-[2-[2-(3-chlorophenyl)-2-hydroxyethylamino]-(2R)-propyl]benzo[d][1,3]dioxole-2,2-dicarboxylate(CL 316,243)

Type

Small organic molecule

Emp. Form.

C20H18ClNO7

Mol. Mass.

419.814

SMILES

C[C@H](Cc1ccc2OC(Oc2c1)(C([O-])=O)C([O-])=O)NC[C@H](O)c1cccc(Cl)c1

Structure