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TargetSelectin E
LigandBDBM50098480
Substrate/Competitorn/a
Meas. Tech.ChEMBL_199704
IC50 5±n/a nM
Citation Stewart AOBhatia PAMcCarty CMPatel MVStaeger MAArendsen DLGunawardana IWMelcher LMZhu GDBoyd SAFry DGCool BLKifle LLartey KMarsh KCKempf-Grote AJKilgannon PWisdom WMeyer JGallatin WMOkasinski GF Discovery of inhibitors of cell adhesion molecule expression in human endothelial cells. 1. Selective inhibition of ICAM-1 and E-selectin expression. J Med Chem 44:988-1002 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Selectin E
Name:Selectin
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:66642.96
Organism:Homo sapiens (Human)
Description:ChEMBL_1438995
Residue:610
Sequence:
MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLN
SILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREK
DVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNC
TALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVV
ECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK
AVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIP
VCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDN
EKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQ
WTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHW
SGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESD
GSYQKPSYIL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50098480
n/a
NameBDBM50098480
Synonyms:4-(4-Bromo-phenylsulfanyl)-thieno[2,3-c]pyridine-2-carboxylic acid amide | CHEMBL266198
TypeSmall organic molecule
Emp. Form.C14H9BrN2OS2
Mol. Mass.365.268
SMILESNC(=O)c1cc2c(Sc3ccc(Br)cc3)cncc2s1
Structure
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