| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
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| Ligand | BDBM50099484 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_153613 |
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| EC50 | 4000±n/a nM |
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| Citation |  Brown, PJ; Stuart, LW; Hurley, KP; Lewis, MC; Winegar, DA; Wilson, JG; Wilkison, WO; Ittoop, OR; Willson, TM Identification of a subtype selective human PPARalpha agonist through parallel-array synthesis. Bioorg Med Chem Lett11:1225-7 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor delta |
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| Name: | Peroxisome proliferator-activated receptor delta |
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| Synonyms: | NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 49910.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q03181 |
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| Residue: | 441 |
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| Sequence: | MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY
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| BDBM50099484 |
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| n/a |
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| Name | BDBM50099484 |
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| Synonyms: | 2-(4-{2-[1-(2-Biphenyl-4-yl-ethyl)-3-(2,4-dimethoxy-phenyl)-ureido]-ethyl}-phenylsulfanyl)-2-methyl-propionic acid | CHEMBL20495 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H38N2O5S |
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| Mol. Mass. | 598.752 |
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| SMILES | COc1ccc(NC(=O)N(CCc2ccc(SC(C)(C)C(O)=O)cc2)CCc2ccc(cc2)-c2ccccc2)c(OC)c1 |
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| Structure | 
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