| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 5 |
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| Ligand | BDBM50197025 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2016534 (CHEMBL4670112) |
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| EC50 | 410±n/a nM |
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| Citation |  Lear, S; Pflimlin, E; Zhou, Z; Huang, D; Weng, S; Nguyen-Tran, V; Joseph, SB; Roller, S; Peterson, S; Li, J; Tremblay, M; Schultz, PG; Shen, W Engineering of a Potent, Long-Acting NPY2R Agonist for Combination with a GLP-1R Agonist as a Multi-Hormonal Treatment for Obesity. J Med Chem63:9660-9671 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 5 |
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| Name: | Neuropeptide Y receptor type 5 |
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| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 50746.64 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15761 |
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| Residue: | 445 |
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| Sequence: | MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNL
LILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFL
QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL
VELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC
GLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAP
ERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIK
KRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCL
NPILYGFLNNGIKADLVSLIHCLHM
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| BDBM50197025 |
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| n/a |
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| Name | BDBM50197025 |
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| Synonyms: | CHEMBL439904 | PYY(3-36) |
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| Type | Small organic molecule |
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| Emp. Form. | C180H279N53O54 |
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| Mol. Mass. | 4049.464 |
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| SMILES | n/a |
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| Structure | 
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