| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
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| Ligand | BDBM50106829 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_39068 |
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| Ki | 4000±n/a nM |
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| Citation |  Gavai, AV; Sher, PM; Mikkilineni, AB; Poss, KM; McCann, PJ; Girotra, RN; Fisher, LG; Wu, G; Bednarz, MS; Mathur, A; Wang, TC; Sun, CQ; Slusarchyk, DA; Skwish, S; Allen, GT; Hillyer, DE; Frohlich, BH; Abboa-Offei, BE; Cap, M; Waldron, TL; George, RJ; Tesfamariam, B; Harper, TW; Ciosek, CP; Young, DA; Dickinson, KE; Seymour, AA; Arbeeny, CM; Washburn, WN BMS-196085: a potent and selective full agonist of the human beta(3) adrenergic receptor. Bioorg Med Chem Lett11:3041-4 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-3 adrenergic receptor |
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| Name: | Beta-3 adrenergic receptor |
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| Synonyms: | ADRB3_MOUSE | Adrb3 | Adrb3r | B3bar | Beta-3 adrenergic receptor | Beta-adrenergic receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43020.18 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_39068 |
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| Residue: | 400 |
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| Sequence: | MAPWPHRNGSLALWSDAPTLDPSAANTSGLPGVPWAAALAGALLALATVGGNLLVIIAIA
RTPRLQTITNVFVTSLAAADLVVGLLVMPPGATLALTGHWPLGETGCELWTSVDVLCVTA
SIETLCALAVDRYLAVTNPLRYGTLVTKRRARAAVVLVWIVSAAVSFAPIMSQWWRVGAD
AEAQECHSNPRCCSFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVAKRQRHLLRRELG
RFSPEESPPSPSRSPSPATGGTPAAPDGVPPCGRRPARLLPLREHRALRTLGLIMGIFSL
CWLPFFLANVLRALAGPSLVPSGVFIALNWLGYANSAFNPVIYCRSPDFRDAFRRLLCSY
GGRGPEEPRAVTFPASPVEARQSPPLNRFDGYEGARPFPT
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| BDBM50106829 |
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| n/a |
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| Name | BDBM50106829 |
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| Synonyms: | BMS-196085 | CHEMBL322862 | N-(5-((R)-2-((R)-1-(4-(difluoromethoxy)phenyl)-2-phenylethylamino)-1-hydroxyethyl)-2-hydroxyphenyl)methanesulfonamide | N-(5-{(R)-2-[(R)-1-(4-Difluoromethoxy-phenyl)-2-phenyl-ethylamino]-1-hydroxy-ethyl}-2-hydroxy-phenyl)-methanesulfonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26F2N2O5S |
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| Mol. Mass. | 492.535 |
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| SMILES | CS(=O)(=O)Nc1cc(ccc1O)[C@@H](O)CN[C@H](Cc1ccccc1)c1ccc(OC(F)F)cc1 |
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| Structure | 
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