| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50121731 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_79946 (CHEMBL689317) |
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| IC50 | 5000±n/a nM |
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| Citation |  Hidaka, K; Kimura, T; Hayashi, Y; McDaniel, KF; Dekhtyar, T; Colletti, L; Kiso, Y Design and synthesis of pseudo-symmetric HIV protease inhibitors containing a novel hydroxymethylcarbonyl (HMC)-hydrazide isostere. Bioorg Med Chem Lett13:93-6 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
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| BDBM50121731 |
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| n/a |
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| Name | BDBM50121731 |
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| Synonyms: | CHEMBL177918 | KNI-1278 | N-[(S)-3-{N-Benzyl-N'-[2-(2,6-dimethyl-phenoxy)-acetyl]-hydrazino}-2-hydroxy-3-oxo-1-((S)-phenylmethyl)-propyl]-2-(2,6-dimethyl-phenoxy)-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C37H41N3O6 |
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| Mol. Mass. | 623.7379 |
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| SMILES | Cc1cccc(C)c1OCC(=O)N[C@@H](Cc1ccccc1)[C@H](O)C(=O)N(Cc1ccccc1)NC(=O)COc1c(C)cccc1C |
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| Structure | 
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