Reaction Details |
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Target | Hypoxanthine-guanine phosphoribosyltransferase |
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Ligand | BDBM50128871 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_90368 (CHEMBL697044) |
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Ki | 600±n/a nM |
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Citation | Medrano, FJ; Wenck, MA; Engel, JC; Craig, SP Analysis of 6-(2,2-Dichloroacetamido)chrysene interaction with the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi. J Med Chem46:2548-50 (2003) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Hypoxanthine-guanine phosphoribosyltransferase |
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Name: | Hypoxanthine-guanine phosphoribosyltransferase |
Synonyms: | HGPRT | HGPRTase | HPRT | HPRT1 | HPRT_HUMAN | Hypoxanthine-guanine phosphoribosyltransferase | Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) |
Type: | Protein |
Mol. Mass.: | 24579.61 |
Organism: | Homo sapiens (Human) |
Description: | P00492 |
Residue: | 218 |
Sequence: | MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH
HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD
DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG
FEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
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BDBM50128871 |
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n/a |
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Name | BDBM50128871 |
Synonyms: | CHEMBL313154 | Chrysen-6-ylamine |
Type | Small organic molecule |
Emp. Form. | C18H13N |
Mol. Mass. | 243.3025 |
SMILES | Nc1cc2c3ccccc3ccc2c2ccccc12 |
Structure |
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