| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
|---|
| Ligand | BDBM50065120 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_215009 |
|---|
| IC50 | 5±n/a nM |
|---|
| Citation |  Sum, FW; Dusza, J; Santos, ED; Grosu, G; Reich, M; Du, X; Albright, JD; Chan, P; Coupet, J; Ru, X; Mazandarani, H; Saunders, T Structure-activity study of novel tricyclic benzazepine arginine vasopressin antagonists. Bioorg Med Chem Lett13:2195-8 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vasopressin V2 receptor |
|---|
| Name: | Vasopressin V2 receptor |
|---|
| Synonyms: | AVPR V2 | Antidiuretic hormone receptor | Avpr2 | Renal-type arginine vasopressin receptor | V2R_RAT | VASOPRESSIN V2 | Vasopressin receptor |
|---|
| Type: | G-protein coupled receptor |
|---|
| Mol. Mass.: | 40761.85 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | n/a |
|---|
| Residue: | 371 |
|---|
| Sequence: | MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLG
ALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQ
RDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGP
SERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEA
PLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCAT
ASSSLMKDTPS
|
|
|
|---|
| BDBM50065120 |
|---|
| n/a |
|---|
| Name | BDBM50065120 |
|---|
| Synonyms: | CHEMBL302709 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-10-carbonyl)-phenyl]-2-chloro-benzamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H20ClN3O2 |
|---|
| Mol. Mass. | 441.909 |
|---|
| SMILES | Clc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
