| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1a receptor |
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| Ligand | BDBM50129476 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_214555 |
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| IC50 | 56.0±n/a nM |
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| Citation |  Sum, FW; Dusza, J; Santos, ED; Grosu, G; Reich, M; Du, X; Albright, JD; Chan, P; Coupet, J; Ru, X; Mazandarani, H; Saunders, T Structure-activity study of novel tricyclic benzazepine arginine vasopressin antagonists. Bioorg Med Chem Lett13:2195-8 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1a receptor |
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| Name: | Vasopressin V1a receptor |
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| Synonyms: | Avpr1a | V1AR_RAT | VASOPRESSIN V1A | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47674.81 |
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| Organism: | RAT |
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| Description: | VASOPRESSIN V1A AVPR1A RAT::P30560 |
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| Residue: | 424 |
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| Sequence: | MSFPRGSQDRSVGNSSPWWPLTTEGSNGSQEAARLGEGDSPLGDVRNEELAKLEIAVLAV
IFVVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQLCWDITYRFRGP
DWLCRVVKHLQVFAMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIATSWVLSFI
LSTPQYFIFSVIEIEVNNGTKTQDCWATFIQPWGTRAYVTWMTSGVFVAPVVVLGTCYGF
ICYHIWRNIRGKTASSRHSKGDKGSGEAVGPFHKGLLVTPCVSSVKSISRAKIRTVKMTF
VIVSAYILCWAPFFIVQMWSVWDENFIWTDSENPSITITALLASLNSCCNPWIYMFFSGH
LLQDCVQSFPCCHSMAQKFAKDDSDSMSRRQTSYSNNRSPTNSTGMWKDSPKSSKSIRFI
PVST
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| BDBM50129476 |
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| n/a |
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| Name | BDBM50129476 |
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| Synonyms: | 2-Methyl-N-[4-(6H-phenanthridine-5-carbonyl)-phenyl]-benzamide | CHEMBL72945 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H22N2O2 |
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| Mol. Mass. | 418.4865 |
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| SMILES | Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2-c2ccccc12 |
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| Structure | 
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