| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen phosphorylase, muscle form |
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| Ligand | BDBM50135567 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_70984 |
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| IC50 | 80±n/a nM |
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| Citation |  Lu, Z; Bohn, J; Bergeron, R; Deng, Q; Ellsworth, KP; Geissler, WM; Harris, G; McCann, PE; McKeever, B; Myers, RW; Saperstein, R; Willoughby, CA; Yao, J; Chapman, K A new class of glycogen phosphorylase inhibitors. Bioorg Med Chem Lett13:4125-8 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycogen phosphorylase, muscle form |
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| Name: | Glycogen phosphorylase, muscle form |
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| Synonyms: | Glycogen phosphorylase, muscle form | Muscle glycogen phosphorylase | Myophosphorylase | PYGM | PYGM_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 97097.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1449751 |
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| Residue: | 842 |
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| Sequence: | MSRPLSDQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTV
RDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDM
EELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEA
DDWLRYGNPWEKARPEFTLPVHFYGHVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVN
TMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFV
VAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDLERM
DWDKAWDVTVRTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFP
GDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKF
QNKTNGITPRRWLVLCNPGLAEVIAERIGEDFISDLDQLRKLLSFVDDEAFIRDVAKVKQ
ENKLKFAAYLEREYKVHINPNSLFDIQVKRIHEYKRQLLNCLHVITLYNRIKREPNKFFV
PRTVMIGGKAAPGYHMAKMIIRLVTAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPA
ADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVD
KLDQRGYNAQEYYDRIPELRQVIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYED
YIKCQEKVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDE
AI
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| BDBM50135567 |
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| n/a |
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| Name | BDBM50135567 |
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| Synonyms: | 4-{3-[(4-Trifluoromethyl-pyridine-2-carbonyl)-amino]-naphthalen-2-yloxy}-phthalic acid | CHEMBL337224 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H15F3N2O6 |
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| Mol. Mass. | 496.3916 |
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| SMILES | OC(=O)c1ccc(Oc2cc3ccccc3cc2NC(=O)c2cc(ccn2)C(F)(F)F)cc1C(O)=O |
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| Structure | 
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