| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen phosphorylase, liver form |
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| Ligand | BDBM50135552 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_70990 |
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| IC50 | 16±n/a nM |
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| Citation |  Lu, Z; Bohn, J; Bergeron, R; Deng, Q; Ellsworth, KP; Geissler, WM; Harris, G; McCann, PE; McKeever, B; Myers, RW; Saperstein, R; Willoughby, CA; Yao, J; Chapman, K A new class of glycogen phosphorylase inhibitors. Bioorg Med Chem Lett13:4125-8 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycogen phosphorylase, liver form |
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| Name: | Glycogen phosphorylase, liver form |
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| Synonyms: | Glycogen phosphorylase, liver form | Lgp | Liver glycogen phosphorylase | PYGL_RAT | Pygl |
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| Type: | PROTEIN |
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| Mol. Mass.: | 97489.46 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1491377 |
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| Residue: | 850 |
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| Sequence: | MAKPLTDQEKRRQISIRGIVGVENVAELKKGFNRHLHFTLVKDRNVATPRDYYFALAHTV
RDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDM
EELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEA
DDWLRHGNPWEKARPEFMLPVHFYGRVEHTQAGTKWVDTQVVLALPYDTPVPGYMNNTVN
TMRLWSARAPNDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFV
VAATLQDVIRRFKASKFGSKDGVGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKL
PWSKAWEITKKTFAYTNHTVLPEALERWPVDLVEKLLPRHLQIIYEINQKHLDRIVALFP
KDIDRMRRMSLIEEEGGKRINMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELEPDKF
QNKTNGITPRRWLLLCNPGLADLIAEKIGEDYVKDLSQLTKLHSFVGDDIFLREIAKVKQ
ENKLKFSQFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIKKDPKKFFV
PRTVIIGGKAAPGYHMAKMIIKLVTSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPA
TDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVA
ALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPNQPDLFKDIINMLFYHDRFKVFADYEA
YVKCQEKVSQLYMNQKAWNTMVLRNIAASGKFSSDRTIREYAKDIWNMEPSDLKISLSKE
SSNGVNANGK
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| BDBM50135552 |
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| n/a |
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| Name | BDBM50135552 |
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| Synonyms: | 4-{2-[(4-Chloro-pyridine-2-carbonyl)-amino]-phenoxy}-phthalic acid | CHEMBL134152 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H13ClN2O6 |
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| Mol. Mass. | 412.78 |
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| SMILES | OC(=O)c1ccc(Oc2ccccc2NC(=O)c2cc(Cl)ccn2)cc1C(O)=O |
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| Structure | 
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