| Reaction Details |
|---|
 | Report a problem with these data |
| Target | RNA-directed RNA polymerase |
|---|
| Ligand | BDBM50137474 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_143777 |
|---|
| IC50 | >500000±n/a nM |
|---|
| Citation |  Beaulieu, PL; Bös, M; Bousquet, Y; Fazal, G; Gauthier, J; Gillard, J; Goulet, S; LaPlante, S; Poupart, MA; Lefebvre, S; McKercher, G; Pellerin, C; Austel, V; Kukolj, G Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives. Bioorg Med Chem Lett14:119-24 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| RNA-directed RNA polymerase |
|---|
| Name: | RNA-directed RNA polymerase |
|---|
| Synonyms: | Hepatitis C virus NS5B RNA-dependent RNA polymerase | NS5B protein |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 25173.95 |
|---|
| Organism: | Hepatitis C virus |
|---|
| Description: | Q8JXU8 |
|---|
| Residue: | 229 |
|---|
| Sequence: | RTEEAIYQCCDLDPQARVAIRSLTERLYVGGPLTNSRGENCGYRRRASGVLTTSCGNTLT
CYIKAQAACRAAGRQDCTMLVCGDDLVVICESAGVQEDAASLRAFTEAMTRYSAPPGDPP
QPEYDLELITSCSSNVSVAHDGAGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIM
FAPTLWVRMIMLTHFFSVLIARDQLEQALDCEIYGACYSIEPLLPPIIQ
|
|
|
|---|
| BDBM50137474 |
|---|
| n/a |
|---|
| Name | BDBM50137474 |
|---|
| Synonyms: | 2-Pyridin-2-yl-1H-benzoimidazole-5-carboxylic acid | CHEMBL174331 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H9N3O2 |
|---|
| Mol. Mass. | 239.2295 |
|---|
| SMILES | OC(=O)c1ccc2nc([nH]c2c1)-c1ccccn1 |
|---|
| Structure | 
|
|---|
Search and Browse
