| Reaction Details |
|---|
 | Report a problem with these data |
| Target | G-protein coupled receptor 35 |
|---|
| Ligand | BDBM50575548 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2125633 (CHEMBL4834978) |
|---|
| IC50 | 48±n/a nM |
|---|
| Citation |  Wei, L; Hou, T; Li, J; Zhang, X; Zhou, H; Wang, Z; Cheng, J; Xiang, K; Wang, J; Zhao, Y; Liang, X Structure-Activity Relationship Studies of Coumarin-like Diacid Derivatives as Human G Protein-Coupled Receptor-35 (hGPR35) Agonists and a Consequent New Design Principle. J Med Chem64:2634-2647 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| G-protein coupled receptor 35 |
|---|
| Name: | G-protein coupled receptor 35 |
|---|
| Synonyms: | G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 34085.57 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_33695097 |
|---|
| Residue: | 309 |
|---|
| Sequence: | MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMT
NLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRH
PLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGF
YLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVR
LAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKS
QDSLCVTLA
|
|
|
|---|
| BDBM50575548 |
|---|
| n/a |
|---|
| Name | BDBM50575548 |
|---|
| Synonyms: | CHEMBL4870213 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H12O9 |
|---|
| Mol. Mass. | 408.3146 |
|---|
| SMILES | COc1ccc(cc1)-c1c2oc(=O)c(cc2cc2cc(C(O)=O)c(=O)oc12)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
