| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase N catalytic chain |
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| Ligand | BDBM50575780 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2125982 (CHEMBL4835327) |
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| Ki | 282000±n/a nM |
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| Citation |  Schaffner, AP; Sansilvestri-Morel, P; Despaux, N; Ruano, E; Persigand, T; Rupin, A; Mennecier, P; Vallez, MO; Raimbaud, E; Desos, P; Gloanec, P Phosphinanes and Azaphosphinanes as Potent and Selective Inhibitors of Activated Thrombin-Activatable Fibrinolysis Inhibitor (TAFIa). J Med Chem64:3897-3910 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase N catalytic chain |
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| Name: | Carboxypeptidase N catalytic chain |
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| Synonyms: | ACBP | Anaphylatoxin inactivator | Arginine carboxypeptidase | CBPN_HUMAN | CPN | CPN1 | Carboxypeptidase N catalytic chain | Carboxypeptidase N polypeptide 1 | Carboxypeptidase N small subunit | Carboxypeptidase N, catalytic subunit | Kininase-1 | Lysine carboxypeptidase | Plasma carboxypeptidase B | SCPN | Serum carboxypeptidase N |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52293.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1496379 |
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| Residue: | 458 |
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| Sequence: | MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHL
YVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQD
TRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN
HHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRT
ASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHT
NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS
VSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIP
QVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
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| BDBM50575780 |
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| n/a |
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| Name | BDBM50575780 |
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| Synonyms: | CHEMBL4878039 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H28FN4O4P |
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| Mol. Mass. | 438.4329 |
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| SMILES | Cn1cncc1-c1cc(F)ccc1CN1CCP(O)(=O)[C@@](CCCCN)(C1)C(O)=O |r| |
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| Structure | 
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