| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50578591 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2133588 (CHEMBL4843198) |
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| EC50 | 0.028184±n/a nM |
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| Citation |  Xing, G; Zhi, Z; Yi, C; Zou, J; Jing, X; Yiu-Ho Woo, A; Lin, B; Pan, L; Zhang, Y; Cheng, M 8-Hydroxyquinolin-2(1H)-one analogues as potential ? Eur J Med Chem224:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50578591 |
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| n/a |
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| Name | BDBM50578591 |
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| Synonyms: | CHEMBL4872653 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22ClF3N2O3 |
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| Mol. Mass. | 442.859 |
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| SMILES | Cl.OC(CNCCCc1cccc(c1)C(F)(F)F)c1ccc(O)c2[nH]c(=O)ccc12 |
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| Structure | 
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