| Reaction Details |
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 | Report a problem with these data |
| Target | Mas-related G-protein coupled receptor member X1 |
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| Ligand | BDBM50583458 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2157377 (CHEMBL5042037) |
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| EC50 | 30000±n/a nM |
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| Citation |  Berhane, I; Hin, N; Thomas, AG; Huang, Q; Zhang, C; Veeravalli, V; Wu, Y; Ng, J; Alt, J; Rojas, C; Hihara, H; Aoki, M; Yoshizawa, K; Nishioka, T; Suzuki, S; He, SQ; Peng, Q; Guan, Y; Dong, X; Raja, SN; Slusher, BS; Rais, R; Tsukamoto, T Thieno[2,3- J Med Chem65:3218-3228 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mas-related G-protein coupled receptor member X1 |
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| Name: | Mas-related G-protein coupled receptor member X1 |
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| Synonyms: | MRGPRX1 | MRGX1 | MRGX1_HUMAN | SNSR3 | SNSR4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36253.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_516621 |
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| Residue: | 322 |
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| Sequence: | MDPTISTLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNA
FSIYILNLAAADFLFLSGRLIYSLLSFISIPHTISKILYPVMMFSYFAGLSFLSAVSTER
CLSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLCGFLFSGADSAWCQTSDFIT
VAWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQFFLFL
WIHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDASE
VDEGGGQLPEEILELSGSRLEQ
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| BDBM50583458 |
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| n/a |
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| Name | BDBM50583458 |
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| Synonyms: | CHEMBL5077884 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H11FN2OS |
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| Mol. Mass. | 274.313 |
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| SMILES | Cc1sc2ncnc(Oc3cccc(F)c3)c2c1C |
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| Structure | 
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