| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mas-related G-protein coupled receptor member X1 |
|---|
| Ligand | BDBM50583460 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2157377 (CHEMBL5042037) |
|---|
| EC50 | 520±n/a nM |
|---|
| Citation |  Berhane, I; Hin, N; Thomas, AG; Huang, Q; Zhang, C; Veeravalli, V; Wu, Y; Ng, J; Alt, J; Rojas, C; Hihara, H; Aoki, M; Yoshizawa, K; Nishioka, T; Suzuki, S; He, SQ; Peng, Q; Guan, Y; Dong, X; Raja, SN; Slusher, BS; Rais, R; Tsukamoto, T Thieno[2,3- J Med Chem65:3218-3228 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mas-related G-protein coupled receptor member X1 |
|---|
| Name: | Mas-related G-protein coupled receptor member X1 |
|---|
| Synonyms: | MRGPRX1 | MRGX1 | MRGX1_HUMAN | SNSR3 | SNSR4 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 36253.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_516621 |
|---|
| Residue: | 322 |
|---|
| Sequence: | MDPTISTLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNA
FSIYILNLAAADFLFLSGRLIYSLLSFISIPHTISKILYPVMMFSYFAGLSFLSAVSTER
CLSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLCGFLFSGADSAWCQTSDFIT
VAWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQFFLFL
WIHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDASE
VDEGGGQLPEEILELSGSRLEQ
|
|
|
|---|
| BDBM50583460 |
|---|
| n/a |
|---|
| Name | BDBM50583460 |
|---|
| Synonyms: | CHEMBL5093049 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H11F3N2OS |
|---|
| Mol. Mass. | 324.321 |
|---|
| SMILES | Cc1sc2ncnc(Oc3ccccc3C(F)(F)F)c2c1C |
|---|
| Structure | 
|
|---|
Search and Browse
