| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50156407 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302834 (CHEMBL876361) |
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| Ki | 11±n/a nM |
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| Citation |  Zhang, D; Kohlman, D; Krushinski, J; Liang, S; Ying, BP; Reilly, JE; Dinn, SR; Wainscott, DB; Nutter, S; Gough, W; Nelson, DL; Schaus, JM; Xu, YC Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists. Bioorg Med Chem Lett14:6011-6 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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| BDBM50156407 |
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| n/a |
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| Name | BDBM50156407 |
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| Synonyms: | 4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-1H-indol-6-yl]-benzamide | CHEMBL361303 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22FN3O |
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| Mol. Mass. | 351.4173 |
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| SMILES | CN1CCC(CC1)n1ccc2ccc(NC(=O)c3ccc(F)cc3)cc12 |
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| Structure | 
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