Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50130461 (4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 167-70 (2003) BindingDB Entry DOI: 10.7270/Q2S46RCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50130461 (4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human 5HT1F receptor by radioligand binding assay | Bioorg Med Chem Lett 25: 4337-41 (2015) Article DOI: 10.1016/j.bmcl.2015.07.042 BindingDB Entry DOI: 10.7270/Q2NC630T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50130461 (4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50156407 (4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-1H-indol-6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50137539 (2,4,6-Trifluoro-N-[3-(1-methyl-piperidin-4-yl)-fur...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 167-70 (2003) BindingDB Entry DOI: 10.7270/Q2S46RCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50137540 (2-Chloro-6-fluoro-N-[3-(1-methyl-piperidin-4-yl)-f...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 167-70 (2003) BindingDB Entry DOI: 10.7270/Q2S46RCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50137538 (2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-f...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 167-70 (2003) BindingDB Entry DOI: 10.7270/Q2S46RCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50137541 (4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-furo[3,2-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Concentration required for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-1) cells expressing the human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 167-70 (2003) BindingDB Entry DOI: 10.7270/Q2S46RCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50156409 (2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50156410 (4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-indazol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50156411 (4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-1H-indazol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM50586388 (CHEMBL5081557) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-25-hydroxycholesterol from His-Flag-tagged human RORgammat LBD (309 to 508 residues) expressed in Escherichia coli measured afte... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01918 BindingDB Entry DOI: 10.7270/Q2B85D1S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50156404 (4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-2,3-dihydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50119543 (CHEMBL3617549) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human 5HT1F receptor by radioligand binding assay | Bioorg Med Chem Lett 25: 4337-41 (2015) Article DOI: 10.1016/j.bmcl.2015.07.042 BindingDB Entry DOI: 10.7270/Q2NC630T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM498074 ((5′S)—N-[4-(Ethylsulfonyl)benzyl]-5′-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-25-hydroxycholesterol from His-Flag-tagged human RORgammat LBD (309 to 508 residues) expressed in Escherichia coli measured afte... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01918 BindingDB Entry DOI: 10.7270/Q2B85D1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50130443 (4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 167-70 (2003) BindingDB Entry DOI: 10.7270/Q2S46RCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50137542 (CHEMBL178066 | N-[3-(2-Dimethylamino-ethyl)-2-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 167-70 (2003) BindingDB Entry DOI: 10.7270/Q2S46RCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50119542 (CHEMBL3617550) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human 5HT1F receptor by radioligand binding assay | Bioorg Med Chem Lett 25: 4337-41 (2015) Article DOI: 10.1016/j.bmcl.2015.07.042 BindingDB Entry DOI: 10.7270/Q2NC630T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50156402 (4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-2,3-dihydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50156402 (4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-2,3-dihydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50119532 (CHEMBL3617557) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human 5HT1F receptor by radioligand binding assay | Bioorg Med Chem Lett 25: 4337-41 (2015) Article DOI: 10.1016/j.bmcl.2015.07.042 BindingDB Entry DOI: 10.7270/Q2NC630T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50156402 (4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-2,3-dihydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 9.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50156407 (4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-1H-indol-6...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50156404 (4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-2,3-dihydr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50156406 (2,4-Difluoro-N-[3-(1-methyl-piperidin-4-yl)-benzo[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50156403 (2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50137537 (CHEMBL369391 | N-[3-(2-Dimethylamino-ethyl)-2-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 167-70 (2003) BindingDB Entry DOI: 10.7270/Q2S46RCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM50586394 (CHEMBL5078351) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-25-hydroxycholesterol from His-Flag-tagged human RORgammat LBD (309 to 508 residues) expressed in Escherichia coli measured afte... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01918 BindingDB Entry DOI: 10.7270/Q2B85D1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM50586395 (CHEMBL5069696) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-25-hydroxycholesterol from His-Flag-tagged human RORgammat LBD (309 to 508 residues) expressed in Escherichia coli measured afte... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01918 BindingDB Entry DOI: 10.7270/Q2B85D1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM50586396 (CHEMBL5079705) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-25-hydroxycholesterol from His-Flag-tagged human RORgammat LBD (309 to 508 residues) expressed in Escherichia coli measured afte... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01918 BindingDB Entry DOI: 10.7270/Q2B85D1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM302860 ((2S)-1-(3-Thienyl)propan-2-ol | US9598431, 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-25-hydroxycholesterol from His-Flag-tagged human RORgammat LBD (309 to 508 residues) expressed in Escherichia coli measured afte... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01918 BindingDB Entry DOI: 10.7270/Q2B85D1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50156408 (2,4,6-Trifluoro-N-[3-(1-methyl-piperidin-4-yl)-2,3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50156412 (4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-benzo[d]is...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50130461 (4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50130461 (4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to 5HT1A receptor (unknown origin) | Bioorg Med Chem Lett 25: 4337-41 (2015) Article DOI: 10.1016/j.bmcl.2015.07.042 BindingDB Entry DOI: 10.7270/Q2NC630T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM50586389 (CHEMBL5093568) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-25-hydroxycholesterol from His-Flag-tagged human RORgammat LBD (309 to 508 residues) expressed in Escherichia coli measured afte... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01918 BindingDB Entry DOI: 10.7270/Q2B85D1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50119540 (CHEMBL3617552) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human 5HT1F receptor by radioligand binding assay | Bioorg Med Chem Lett 25: 4337-41 (2015) Article DOI: 10.1016/j.bmcl.2015.07.042 BindingDB Entry DOI: 10.7270/Q2NC630T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM50586393 (CHEMBL5077159) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-25-hydroxycholesterol from His-Flag-tagged human RORgammat LBD (309 to 508 residues) expressed in Escherichia coli measured afte... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01918 BindingDB Entry DOI: 10.7270/Q2B85D1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM50586397 (CHEMBL5092218) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 139 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-25-hydroxycholesterol from His-Flag-tagged human RORgammat LBD (309 to 508 residues) expressed in Escherichia coli measured afte... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01918 BindingDB Entry DOI: 10.7270/Q2B85D1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50156407 (4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-1H-indol-6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50156412 (4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-benzo[d]is...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50156404 (4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-2,3-dihydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50130461 (4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1B receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM50586391 (CHEMBL5085419) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 249 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-25-hydroxycholesterol from His-Flag-tagged human RORgammat LBD (309 to 508 residues) expressed in Escherichia coli measured afte... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01918 BindingDB Entry DOI: 10.7270/Q2B85D1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM50586390 (CHEMBL5081257) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 249 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-25-hydroxycholesterol from His-Flag-tagged human RORgammat LBD (309 to 508 residues) expressed in Escherichia coli measured afte... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01918 BindingDB Entry DOI: 10.7270/Q2B85D1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50156402 (4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-2,3-dihydr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50156402 (4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-2,3-dihydr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50156407 (4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-1H-indol-6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1B receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM50586392 (CHEMBL5082586) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 278 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-25-hydroxycholesterol from His-Flag-tagged human RORgammat LBD (309 to 508 residues) expressed in Escherichia coli measured afte... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01918 BindingDB Entry DOI: 10.7270/Q2B85D1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50156411 (4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-1H-indazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK | |||||||||||
More data for this Ligand-Target Pair |
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