Compile Data Set for Download or QSAR

Found 257 hits with Last Name = 'krushinski' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM84745 (CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...) Show SMILES CNCC[C@H](Oc1cccc2ccccc12)c1cccs1 |r| Show InChI InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP Ki Database									Neuropsychopharmacology 8: 23-33 (1993) Article DOI: 10.1038/npp.1993.4 BindingDB Entry DOI: 10.7270/Q2XS5SXF
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50019443 (1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...) Show SMILES CC(C)NCC(O)COc1cccc2[nH]ccc12 Show InChI InChI=1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity at human adrenergic beta2 receptor				Bioorg Med Chem Lett 17: 5600-4 (2007) Article DOI: 10.1016/j.bmcl.2007.07.086 BindingDB Entry DOI: 10.7270/Q2FJ2GG0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50073686 (CHEMBL423029 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...) Show SMILES CN(C)CCc1c[nH]c2ccc(cc12)C(C)(C)C Show InChI InChI=1S/C16H24N2/c1-16(2,3)13-6-7-15-14(10-13)12(11-17-15)8-9-18(4)5/h6-7,10-11,17H,8-9H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50073688 (CHEMBL357034 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...) Show SMILES CNCCc1c[nH]c2ccc(cc12)C(C)(C)C Show InChI InChI=1S/C15H22N2/c1-15(2,3)12-5-6-14-13(9-12)11(10-17-14)7-8-16-4/h5-6,9-10,16-17H,7-8H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50019443 (1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol ...) Show SMILES CC(C)NCC(O)COc1cccc2[nH]ccc12 Show InChI InChI=1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity at human adrenergic beta1 receptor				Bioorg Med Chem Lett 17: 5600-4 (2007) Article DOI: 10.1016/j.bmcl.2007.07.086 BindingDB Entry DOI: 10.7270/Q2FJ2GG0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50228247 (CHEMBL38017 | LY-197055) Show SMILES CC1CC(=O)NN=C1c1ccc2NC(=O)C(C)(C)c2c1 |c:6| Show InChI InChI=1S/C15H17N3O2/c1-8-6-12(19)17-18-13(8)9-4-5-11-10(7-9)15(2,3)14(20)16-11/h4-5,7-8H,6H2,1-3H3,(H,16,20)(H,17,19)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement [3H]LY-186,126 from phosphodiesterase 4 of myocardial vesicles				J Med Chem 32: 1476-80 (1989) BindingDB Entry DOI: 10.7270/Q2P271B2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50073684 (2-(5-tert-Butyl-1H-indol-3-yl)-ethylamine | CHEMBL...) Show SMILES CC(C)(C)c1ccc2[nH]cc(CCN)c2c1 Show InChI InChI=1S/C14H20N2/c1-14(2,3)11-4-5-13-12(8-11)10(6-7-15)9-16-13/h4-5,8-9,16H,6-7,15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50136685 (CHEMBL337822 | [3-Furan-2-yl-3-(naphthalen-1-yloxy...) Show SMILES CNCCC(Oc1cccc2ccccc12)c1ccco1 Show InChI InChI=1S/C18H19NO2/c1-19-12-11-18(17-10-5-13-20-17)21-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,18-19H,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM84745 (CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...) Show SMILES CNCC[C@H](Oc1cccc2ccccc12)c1cccs1 |r| Show InChI InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to inhibit the reuptake of 5-HT at human serotonin transporter				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50136672 (CHEMBL342716 | [3-(4-Fluoro-phenyl)-3-(naphthalen-...) Show SMILES CNCCC(Oc1cccc2ccccc12)c1ccc(F)cc1 Show InChI InChI=1S/C20H20FNO/c1-22-14-13-19(16-9-11-17(21)12-10-16)23-20-8-4-6-15-5-2-3-7-18(15)20/h2-12,19,22H,13-14H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50136683 (CHEMBL142028 | Methyl-[3-(naphthalen-1-yloxy)-3-th...) Show SMILES CNCCC(Oc1cccc2ccccc12)c1ccsc1 Show InChI InChI=1S/C18H19NOS/c1-19-11-9-17(15-10-12-21-13-15)20-18-8-4-6-14-5-2-3-7-16(14)18/h2-8,10,12-13,17,19H,9,11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50073687 (2-(5-Isopropyl-1H-indol-3-yl)-ethylamine | CHEMBL1...) Show SMILES CC(C)c1ccc2[nH]cc(CCN)c2c1 Show InChI InChI=1S/C13H18N2/c1-9(2)10-3-4-13-12(7-10)11(5-6-14)8-15-13/h3-4,7-9,15H,5-6,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50220910 ((S)-1-(1H-indol-4-yloxy)-3-(cyclohexylamino)propan...) Show SMILES O[C@@H](CNC1CCCCC1)COc1cccc2[nH]ccc12 Show InChI InChI=1S/C17H24N2O2/c20-14(11-19-13-5-2-1-3-6-13)12-21-17-8-4-7-16-15(17)9-10-18-16/h4,7-10,13-14,18-20H,1-3,5-6,11-12H2/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]DPAT from human 5HT1A receptor				Bioorg Med Chem Lett 17: 5600-4 (2007) Article DOI: 10.1016/j.bmcl.2007.07.086 BindingDB Entry DOI: 10.7270/Q2FJ2GG0
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50136680 (CHEMBL424660 | N-methyl-3-(1-naphthyloxy)-3-(2-thi...) Show SMILES CNCCC(Oc1cccc2ccccc12)c1cccs1 Show InChI InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50073681 (2-(5-Cyclopentyl-1H-indol-3-yl)-ethylamine | CHEMB...) Show SMILES NCCc1c[nH]c2ccc(cc12)C1CCCC1 Show InChI InChI=1S/C15H20N2/c16-8-7-13-10-17-15-6-5-12(9-14(13)15)11-3-1-2-4-11/h5-6,9-11,17H,1-4,7-8,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50073688 (CHEMBL357034 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...) Show SMILES CNCCc1c[nH]c2ccc(cc12)C(C)(C)C Show InChI InChI=1S/C15H22N2/c1-15(2,3)12-5-6-14-13(9-12)11(10-17-14)7-8-16-4/h5-6,9-10,16-17H,7-8H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50136679 (CHEMBL141741 | Methyl-[3-(naphthalen-1-yloxy)-3-o-...) Show SMILES CNCCC(Oc1cccc2ccccc12)c1ccccc1C Show InChI InChI=1S/C21H23NO/c1-16-8-3-5-11-18(16)21(14-15-22-2)23-20-13-7-10-17-9-4-6-12-19(17)20/h3-13,21-22H,14-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50136689 (CHEMBL141114 | Methyl-[3-(naphthalen-1-yloxy)-3-p-...) Show SMILES CNCCC(Oc1cccc2ccccc12)c1ccc(C)cc1 Show InChI InChI=1S/C21H23NO/c1-16-10-12-18(13-11-16)20(14-15-22-2)23-21-9-5-7-17-6-3-4-8-19(17)21/h3-13,20,22H,14-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1F (Homo sapiens (Human))	BDBM50130461 (4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...) Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C21H22FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12-14,23H,8-11H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human 5HT1F receptor by radioligand binding assay				Bioorg Med Chem Lett 25: 4337-41 (2015) Article DOI: 10.1016/j.bmcl.2015.07.042 BindingDB Entry DOI: 10.7270/Q2NC630T
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1F (Homo sapiens (Human))	BDBM50130461 (4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...) Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C21H22FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12-14,23H,8-11H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor				Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50136690 (CHEMBL337791 | [3-(3-Methoxy-phenyl)-3-(naphthalen...) Show SMILES CNCCC(Oc1cccc2ccccc12)c1cccc(OC)c1 Show InChI InChI=1S/C21H23NO2/c1-22-14-13-20(17-9-5-10-18(15-17)23-2)24-21-12-6-8-16-7-3-4-11-19(16)21/h3-12,15,20,22H,13-14H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1F (Homo sapiens (Human))	BDBM50156407 (4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-1H-indol-6...) Show SMILES CN1CCC(CC1)n1ccc2ccc(NC(=O)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C21H22FN3O/c1-24-11-9-19(10-12-24)25-13-8-15-4-7-18(14-20(15)25)23-21(26)16-2-5-17(22)6-3-16/h2-8,13-14,19H,9-12H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor				Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50136691 (CHEMBL139106 | [3-(2-Methoxy-phenyl)-3-(naphthalen...) Show SMILES CNCCC(Oc1cccc2ccccc12)c1ccccc1OC Show InChI InChI=1S/C21H23NO2/c1-22-15-14-21(18-11-5-6-12-19(18)23-2)24-20-13-7-9-16-8-3-4-10-17(16)20/h3-13,21-22H,14-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50073682 (CHEMBL1278 | N-methyl-2-(3-(1-methylpiperiden-4-yl...) Show SMILES CNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1 Show InChI InChI=1S/C17H25N3O2S/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14/h3-4,11-12,14,18-19H,5-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	DrugBank Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50136682 (CHEMBL141681 | Methyl-[3-(naphthalen-1-yloxy)-3-ph...) Show SMILES CNCCC(Oc1cccc2ccccc12)c1ccccc1 Show InChI InChI=1S/C20H21NO/c1-21-15-14-19(17-9-3-2-4-10-17)22-20-13-7-11-16-8-5-6-12-18(16)20/h2-13,19,21H,14-15H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50220910 ((S)-1-(1H-indol-4-yloxy)-3-(cyclohexylamino)propan...) Show SMILES O[C@@H](CNC1CCCCC1)COc1cccc2[nH]ccc12 Show InChI InChI=1S/C17H24N2O2/c20-14(11-19-13-5-2-1-3-6-13)12-21-17-8-4-7-16-15(17)9-10-18-16/h4,7-10,13-14,18-20H,1-3,5-6,11-12H2/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity at human adrenergic beta1 receptor				Bioorg Med Chem Lett 17: 5600-4 (2007) Article DOI: 10.1016/j.bmcl.2007.07.086 BindingDB Entry DOI: 10.7270/Q2FJ2GG0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50073682 (CHEMBL1278 | N-methyl-2-(3-(1-methylpiperiden-4-yl...) Show SMILES CNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1 Show InChI InChI=1S/C17H25N3O2S/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14/h3-4,11-12,14,18-19H,5-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	DrugBank Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50073690 (2-(5-Cyclohexyl-1H-indol-3-yl)-ethylamine | CHEMBL...) Show SMILES NCCc1c[nH]c2ccc(cc12)C1CCCCC1 Show InChI InChI=1S/C16H22N2/c17-9-8-14-11-18-16-7-6-13(10-15(14)16)12-4-2-1-3-5-12/h6-7,10-12,18H,1-5,8-9,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50136686 (CHEMBL415244 | [3-(4-Methoxy-phenyl)-3-(naphthalen...) Show SMILES CNCCC(Oc1cccc2ccccc12)c1ccc(OC)cc1 Show InChI InChI=1S/C21H23NO2/c1-22-15-14-20(17-10-12-18(23-2)13-11-17)24-21-9-5-7-16-6-3-4-8-19(16)21/h3-13,20,22H,14-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50220914 (1-(1H-indol-4-yloxy)-3-(cyclohexylamino)propan-2-o...) Show SMILES OC(CNC1CCCCC1)COc1cccc2[nH]ccc12 |w:1.0| Show InChI InChI=1S/C17H24N2O2/c20-14(11-19-13-5-2-1-3-6-13)12-21-17-8-4-7-16-15(17)9-10-18-16/h4,7-10,13-14,18-20H,1-3,5-6,11-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]DPAT from human 5HT1A receptor				Bioorg Med Chem Lett 17: 5600-4 (2007) Article DOI: 10.1016/j.bmcl.2007.07.086 BindingDB Entry DOI: 10.7270/Q2FJ2GG0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1F (Homo sapiens (Human))	BDBM50156409 (2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-b...) Show SMILES CN1CCC(CC1)c1noc2ccc(NC(=O)c3ccc(F)cc3Cl)cc12 Show InChI InChI=1S/C20H19ClFN3O2/c1-25-8-6-12(7-9-25)19-16-11-14(3-5-18(16)27-24-19)23-20(26)15-4-2-13(22)10-17(15)21/h2-5,10-12H,6-9H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor				Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50049086 (2-(5-Ethyl-1H-indol-3-yl)-ethylamine | CHEMBL10751...) Show SMILES CCc1ccc2[nH]cc(CCN)c2c1 Show InChI InChI=1S/C12H16N2/c1-2-9-3-4-12-11(7-9)10(5-6-13)8-14-12/h3-4,7-8,14H,2,5-6,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50220910 ((S)-1-(1H-indol-4-yloxy)-3-(cyclohexylamino)propan...) Show SMILES O[C@@H](CNC1CCCCC1)COc1cccc2[nH]ccc12 Show InChI InChI=1S/C17H24N2O2/c20-14(11-19-13-5-2-1-3-6-13)12-21-17-8-4-7-16-15(17)9-10-18-16/h4,7-10,13-14,18-20H,1-3,5-6,11-12H2/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity at human adrenergic beta2 receptor				Bioorg Med Chem Lett 17: 5600-4 (2007) Article DOI: 10.1016/j.bmcl.2007.07.086 BindingDB Entry DOI: 10.7270/Q2FJ2GG0
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50136688 (CHEMBL139245 | [3-(4-Chloro-phenyl)-3-(naphthalen-...) Show SMILES CNCCC(Oc1cccc2ccccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H20ClNO/c1-22-14-13-19(16-9-11-17(21)12-10-16)23-20-8-4-6-15-5-2-3-7-18(15)20/h2-12,19,22H,13-14H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1F (Homo sapiens (Human))	BDBM50156410 (4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-indazol...) Show SMILES CN1CCC(CC1)c1n[nH]c2ccc(NC(=O)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C20H21FN4O/c1-25-10-8-13(9-11-25)19-17-12-16(6-7-18(17)23-24-19)22-20(26)14-2-4-15(21)5-3-14/h2-7,12-13H,8-11H2,1H3,(H,22,26)(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor				Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50220911 ((S)-1-(adamantan-1-ylamino)-3-(1H-indol-4-yloxy)-p...) Show SMILES O[C@@H](CNC12CC3CC(CC(C3)C1)C2)COc1cccc2[nH]ccc12 |TLB:3:4:7:11.9.10,THB:9:8:5:11.10.12,9:10:7.8.13:5,12:10:7:13.4.5,12:4:7:11.9.10| Show InChI InChI=1S/C21H28N2O2/c24-17(13-25-20-3-1-2-19-18(20)4-5-22-19)12-23-21-9-14-6-15(10-21)8-16(7-14)11-21/h1-5,14-17,22-24H,6-13H2/t14?,15?,16?,17-,21?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]DPAT from human 5HT1A receptor				Bioorg Med Chem Lett 17: 5600-4 (2007) Article DOI: 10.1016/j.bmcl.2007.07.086 BindingDB Entry DOI: 10.7270/Q2FJ2GG0
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50136675 (CHEMBL139277 | Methyl-[3-(naphthalen-1-yloxy)-3-m-...) Show SMILES CNCCC(Oc1cccc2ccccc12)c1cccc(C)c1 Show InChI InChI=1S/C21H23NO/c1-16-7-5-10-18(15-16)20(13-14-22-2)23-21-12-6-9-17-8-3-4-11-19(17)21/h3-12,15,20,22H,13-14H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1F (Homo sapiens (Human))	BDBM50156411 (4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-1H-indazol...) Show SMILES CN1CCC(CC1)n1ncc2ccc(NC(=O)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C20H21FN4O/c1-24-10-8-18(9-11-24)25-19-12-17(7-4-15(19)13-22-25)23-20(26)14-2-5-16(21)6-3-14/h2-7,12-13,18H,8-11H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor				Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50136676 (CHEMBL139168 | [3-(4-Bromo-phenyl)-3-(naphthalen-1...) Show SMILES CNCCC(Oc1cccc2ccccc12)c1ccc(Br)cc1 Show InChI InChI=1S/C20H20BrNO/c1-22-14-13-19(16-9-11-17(21)12-10-16)23-20-8-4-6-15-5-2-3-7-18(15)20/h2-12,19,22H,13-14H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand				Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50033437 (CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...) Show SMILES CN(C)CCc1c[nH]c2ccc(Cn3cncn3)cc12 Show InChI InChI=1S/C15H19N5/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50005835 ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) Show SMILES CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	DrugBank Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50073689 ((R)-6-Methylamino-6,7,8,9-tetrahydro-5H-carbazole-...) Show SMILES CN[C@@H]1CCc2[nH]c3ccc(cc3c2C1)C(N)=O Show InChI InChI=1S/C14H17N3O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18)/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM84745 (CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...) Show SMILES CNCC[C@H](Oc1cccc2ccccc12)c1cccs1 |r| Show InChI InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP Ki Database									Neuropsychopharmacology 8: 23-33 (1993) Article DOI: 10.1038/npp.1993.4 BindingDB Entry DOI: 10.7270/Q2XS5SXF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50220911 ((S)-1-(adamantan-1-ylamino)-3-(1H-indol-4-yloxy)-p...) Show SMILES O[C@@H](CNC12CC3CC(CC(C3)C1)C2)COc1cccc2[nH]ccc12 |TLB:3:4:7:11.9.10,THB:9:8:5:11.10.12,9:10:7.8.13:5,12:10:7:13.4.5,12:4:7:11.9.10| Show InChI InChI=1S/C21H28N2O2/c24-17(13-25-20-3-1-2-19-18(20)4-5-22-19)12-23-21-9-14-6-15(10-21)8-16(7-14)11-21/h1-5,14-17,22-24H,6-13H2/t14?,15?,16?,17-,21?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human 5HT1A expressed in mouse LM(tK-) cells assessed as inhibition of 5HT-stimulated [35S]GTPgammaS binding				Bioorg Med Chem Lett 17: 5600-4 (2007) Article DOI: 10.1016/j.bmcl.2007.07.086 BindingDB Entry DOI: 10.7270/Q2FJ2GG0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1F (Homo sapiens (Human))	BDBM50156404 (4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-2,3-dihydr...) Show SMILES CN1CCC(CC1)N1CCc2ccc(NC(=O)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C21H24FN3O/c1-24-11-9-19(10-12-24)25-13-8-15-4-7-18(14-20(15)25)23-21(26)16-2-5-17(22)6-3-16/h2-7,14,19H,8-13H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1F receptor				Bioorg Med Chem Lett 14: 6011-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.079 BindingDB Entry DOI: 10.7270/Q23J3CFK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1F (Homo sapiens (Human))	BDBM50119543 (CHEMBL3617549) Show SMILES CN1CCC(CC1)C(=O)c1cccc(NC(=O)c2ccc(F)cc2)c1 Show InChI InChI=1S/C20H21FN2O2/c1-23-11-9-14(10-12-23)19(24)16-3-2-4-18(13-16)22-20(25)15-5-7-17(21)8-6-15/h2-8,13-14H,9-12H2,1H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human 5HT1F receptor by radioligand binding assay				Bioorg Med Chem Lett 25: 4337-41 (2015) Article DOI: 10.1016/j.bmcl.2015.07.042 BindingDB Entry DOI: 10.7270/Q2NC630T
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50228246 (Indolidan) Show SMILES CC1(C)C(=O)Nc2ccc(cc12)C1=NNC(=O)CC1 |t:14| Show InChI InChI=1S/C14H15N3O2/c1-14(2)9-7-8(3-4-11(9)15-13(14)19)10-5-6-12(18)17-16-10/h3-4,7H,5-6H2,1-2H3,(H,15,19)(H,17,18)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement [3H]LY-186,126 from phosphodiesterase 4 of myocardial vesicles				J Med Chem 32: 1476-80 (1989) BindingDB Entry DOI: 10.7270/Q2P271B2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50073688 (CHEMBL357034 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...) Show SMILES CNCCc1c[nH]c2ccc(cc12)C(C)(C)C Show InChI InChI=1S/C15H22N2/c1-15(2,3)12-5-6-14-13(9-12)11(10-17-14)7-8-16-4/h5-6,9-10,16-17H,7-8H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50073685 (CHEMBL147454 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...) Show SMILES CCCNCCc1c[nH]c2ccc(cc12)C(C)(C)C Show InChI InChI=1S/C17H26N2/c1-5-9-18-10-8-13-12-19-16-7-6-14(11-15(13)16)17(2,3)4/h6-7,11-12,18-19H,5,8-10H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor				J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 257 total )  |  Next  |  Last  >>

Jump to: