| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50156904 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_429830 (CHEMBL915411) |
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| Ki | 530±n/a nM |
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| Citation |  Merabet, N; Dumond, J; Collinet, B; Van Baelinghem, L; Boggetto, N; Ongeri, S; Ressad, F; Reboud-Ravaux, M; Sicsic, S New constrained"molecular tongs" designed to dissociate HIV-1 protease dimer. J Med Chem47:6392-400 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50156904 |
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| n/a |
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| Name | BDBM50156904 |
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| Synonyms: | (S)-tert-butyl 5-((S)-1-amino-4-methyl-1-oxopentan-2-ylamino)-4-(4-(7-(4-((S)-1-((S)-1-((S)-1-methoxy-3-methyl-1-oxobutan-2-ylamino)-4-methyl-1-oxopentan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-4-oxobutoxy)quinolin-2-yloxy)butanamido)-5-oxopentanoate | CHEMBL267184 |
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| Type | Small organic molecule |
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| Emp. Form. | C49H77N7O12 |
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| Mol. Mass. | 956.1754 |
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| SMILES | COC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)CCCOc1ccc2ccc(OCCCC(=O)N[C@@H](CCC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O)nc2c1)C(C)C)C(C)C |r| |
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| Structure | 
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