| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 5 |
|---|
| Ligand | BDBM50186382 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_377653 (CHEMBL863682) |
|---|
| EC50 | 200±n/a nM |
|---|
| Citation |  Vachal, P; Toth, LM; Hale, JJ; Yan, L; Mills, SG; Chrebet, GL; Koehane, CA; Hajdu, R; Milligan, JA; Rosenbach, MJ; Mandala, S Highly selective and potent agonists of sphingosine-1-phosphate 1 (S1P1) receptor. Bioorg Med Chem Lett16:3684-7 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sphingosine 1-phosphate receptor 5 |
|---|
| Name: | Sphingosine 1-phosphate receptor 5 |
|---|
| Synonyms: | EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 41796.42 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 398 |
|---|
| Sequence: | MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
|
|
|
|---|
| BDBM50186382 |
|---|
| n/a |
|---|
| Name | BDBM50186382 |
|---|
| Synonyms: | 3-(4-(2-(3-cyano-4-isopropoxyphenyl)thiazol-5-yl)-3-methylphenyl)propanoic acid | CHEMBL379612 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H22N2O3S |
|---|
| Mol. Mass. | 406.497 |
|---|
| SMILES | CC(C)Oc1ccc(cc1C#N)-c1ncc(s1)-c1ccc(CCC(O)=O)cc1C |
|---|
| Structure | 
|
|---|
Search and Browse
