Reaction Details |
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Target | Low molecular weight phosphotyrosine protein phosphatase |
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Ligand | BDBM50188779 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_389280 (CHEMBL868036) |
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IC50 | 4800±n/a nM |
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Citation | Amarasinghe, KK; Evdokimov, AG; Evidokimov, AG; Xu, K; Clark, CM; Maier, MB; Srivastava, A; Colson, AO; Gerwe, GS; Stake, GE; Howard, BW; Pokross, ME; Gray, JL; Peters, KG Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta. Bioorg Med Chem Lett16:4252-6 (2006) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Low molecular weight phosphotyrosine protein phosphatase |
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Name: | Low molecular weight phosphotyrosine protein phosphatase |
Synonyms: | 3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c |
Type: | n/a |
Mol. Mass.: | 18042.81 |
Organism: | Homo sapiens (Human) |
Description: | P24666 |
Residue: | 158 |
Sequence: | MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
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BDBM50188779 |
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n/a |
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Name | BDBM50188779 |
Synonyms: | CHEMBL378423 | ammonium N-{4-[4-ethoxy-2,2-bis(methoxycarbonyl)-4-oxobutyl]phenyl}sulfamate |
Type | Small organic molecule |
Emp. Form. | C16H20NO9S |
Mol. Mass. | 402.397 |
SMILES | CCOC(=O)CC(Cc1ccc(NS([O-])(=O)=O)cc1)(C(=O)OC)C(=O)OC |
Structure |
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