| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 4B1 |
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| Ligand | BDBM50607543 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2262943 (CHEMBL5217954) |
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| IC50 | >100000±n/a nM |
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| Citation |  Barrows, RD; Jeffries, DE; Vishe, M; Tukachinsky, H; Zheng, SL; Li, F; Ma, Z; Li, X; Jin, S; Song, H; Zhang, R; Zhang, S; Ni, J; Luan, H; Wen, L; Rongshan, Y; Ying, C; Shair, MD Potent Uncompetitive Inhibitors of Nicotinamide J Med Chem65:14642-14654 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 4B1 |
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| Name: | Cytochrome P450 4B1 |
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| Synonyms: | 1.14.14.1 | CP4B1_HUMAN | CYP4B1 | CYPIVB1 | Cytochrome P450 4B1 | Cytochrome P450-HP |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59005.59 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_119703 |
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| Residue: | 511 |
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| Sequence: | MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE
IQETGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQ
WIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDI
FCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT
PHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKL
SDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDL
GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWP
DPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDP
SRLPIKMPQLVLRSKNGFHLHLKPLGPGSGK
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| BDBM50607543 |
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| n/a |
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| Name | BDBM50607543 |
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| Synonyms: | CHEMBL5220590 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H11N3O |
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| Mol. Mass. | 177.2031 |
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| SMILES | C[C@@H]1Cc2cc(cnc2N1)C(N)=O |r| |
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| Structure | 
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