| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase N catalytic chain |
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| Ligand | BDBM50201438 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_452078 (CHEMBL901239) |
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| Ki | 2±n/a nM |
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| Citation |  Bunnage, ME; Blagg, J; Steele, J; Owen, DR; Allerton, C; McElroy, AB; Miller, D; Ringer, T; Butcher, K; Beaumont, K; Evans, K; Gray, AJ; Holland, SJ; Feeder, N; Moore, RS; Brown, DG Discovery of potent& selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis. J Med Chem50:6095-103 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase N catalytic chain |
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| Name: | Carboxypeptidase N catalytic chain |
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| Synonyms: | ACBP | Anaphylatoxin inactivator | Arginine carboxypeptidase | CBPN_HUMAN | CPN | CPN1 | Carboxypeptidase N catalytic chain | Carboxypeptidase N polypeptide 1 | Carboxypeptidase N small subunit | Carboxypeptidase N, catalytic subunit | Kininase-1 | Lysine carboxypeptidase | Plasma carboxypeptidase B | SCPN | Serum carboxypeptidase N |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52293.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1496379 |
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| Residue: | 458 |
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| Sequence: | MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHL
YVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQD
TRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN
HHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRT
ASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHT
NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS
VSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIP
QVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
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| BDBM50201438 |
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| n/a |
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| Name | BDBM50201438 |
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| Synonyms: | (+/-)-5-guanidino-2-(mercaptomethyl)pentanoic acid | 5-guanidino-2-(mercaptomethyl)pentanoic acid | CHEMBL236822 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H15N3O2S |
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| Mol. Mass. | 205.278 |
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| SMILES | [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6](-[#6]-[#16])-[#6](-[#8])=O |
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| Structure | 
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