| Reaction Details |
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 | Report a problem with these data |
| Target | DNA polymerase beta |
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| Ligand | BDBM50242105 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_550598 (CHEMBL999199) |
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| IC50 | 12300±n/a nM |
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| Citation |  Prakash Chaturvedula, VS; Hecht, SM; Gao, Z; Jones, SH; Feng, X; Kingston, DG New neolignans that inhibit DNA polymerase beta lyase. J Nat Prod67:964-7 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA polymerase beta |
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| Name: | DNA polymerase beta |
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| Synonyms: | DNA polymerase beta (Pol β) | DPOLB_HUMAN | POLB |
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| Type: | Protein |
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| Mol. Mass.: | 38188.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 335 |
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| Sequence: | MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
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| BDBM50242105 |
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| n/a |
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| Name | BDBM50242105 |
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| Synonyms: | CHEMBL470873 | armenin-B |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24O6 |
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| Mol. Mass. | 372.4117 |
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| SMILES | CO[C@@H]1C[C@]2(CC=C)[C@H](C)[C@H](OC2=C(OC)C1=O)c1ccc2OCOc2c1 |r,t:13| |
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| Structure | 
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