| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 5 |
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| Ligand | BDBM50254849 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_559919 (CHEMBL1013713) |
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| IC50 | 200±n/a nM |
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| Citation |  Vaccaro, W; Huynh, T; Lloyd, J; Atwal, K; Finlay, HJ; Levesque, P; Conder, ML; Jenkins-West, T; Shi, H; Sun, L Dihydropyrazolopyrimidine inhibitors of K(V)1.5 (I(Kur)). Bioorg Med Chem Lett18:6381-5 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 5 |
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| Name: | Potassium voltage-gated channel subfamily A member 5 |
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| Synonyms: | HK2 | HPCN1 | KCNA5 | KCNA5_HUMAN | Potassium voltage-gated channel subfamily A member 5 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.5 |
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| Type: | Enzyme |
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| Mol. Mass.: | 67222.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22460 |
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| Residue: | 613 |
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| Sequence: | MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDA
DSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQ
RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQ
SGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIF
EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG
SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII
DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGL
QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT
VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG
TQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSL
YALCLDTSRETDL
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| BDBM50254849 |
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| n/a |
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| Name | BDBM50254849 |
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| Synonyms: | (4-(4-fluorophenyl)piperazin-1-yl)(5-methyl-7-(3-methylbenzo[b]thiophen-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)methanone | CHEMBL481399 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H26FN5OS |
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| Mol. Mass. | 487.592 |
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| SMILES | Cc1c(sc2ccccc12)C1C(C(=O)N2CCN(CC2)c2ccc(F)cc2)C(C)=Nc2ccnn12 |c:32| |
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| Structure | 
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