| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor B |
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| Ligand | BDBM50282263 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_34830 (CHEMBL648764) |
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| IC50 | 7.6±n/a nM |
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| Citation |  Perreaut, P; Clément, J; Muneaux, C; Muneaux, Y; Cazaubon, C; Gougat, J; Guiraudou, P; Lacour, C; Nisato, D; Fur, GL; Breliere, JC Dihydro-imidazolone derivatives as angiotensin II receptor antagonists: chiral effect on the activity Bioorg Med Chem Lett4:163-168 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor B |
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| Name: | Type-1 angiotensin II receptor B |
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| Synonyms: | AGTRB_RAT | AT3 | Agtr1 | Agtr1b | Angiotensin II AT1B | Angiotensin II receptor (AT-1) type-1 | Angiotensin II type 1b (AT-1b) receptor | At1b | Type-1B angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40929.44 |
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| Organism: | RAT |
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| Description: | Angiotensin II AT1B 0 RAT::P29089 |
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| Residue: | 359 |
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| Sequence: | MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
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| BDBM50282263 |
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| n/a |
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| Name | BDBM50282263 |
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| Synonyms: | 2-Butyl-5-cyclopentyl-5-methyl-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,5-dihydro-imidazol-4-one | CHEMBL47985 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H32N6O |
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| Mol. Mass. | 456.5826 |
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| SMILES | CCCCC1=NC(C)(C2CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| |
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| Structure | 
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