| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50282326 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_36947 |
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| IC50 | 16±n/a nM |
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| Citation |  Kim, D; Mantlo, NB; Tata, JR; Fitch, K; Dhanoa, D; Owens, K; Levorse, D; Siegl, PK; Chang, RS; Chen, T; Scheck, S; Zingaro, GJ; Kivlighn, SD; Greenlee, WJ Acidic phenols: a new class of potent nonpeptide angiotensin II receptor antagonists Bioorg Med Chem Lett4:207-212 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41009.15 |
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| Organism: | RABBIT |
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| Description: | ANGIOTENSIN AT1 AGTR1 RABBIT::P34976 |
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| Residue: | 359 |
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| Sequence: | MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
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| BDBM50282326 |
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| n/a |
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| Name | BDBM50282326 |
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| Synonyms: | 2,6-Dichloro-4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenol | CHEMBL63144 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17Cl2N3O |
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| Mol. Mass. | 350.242 |
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| SMILES | CCc1nc2c(C)cc(C)nc2n1Cc1cc(Cl)c(O)c(Cl)c1 |
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| Structure | 
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