Compile Data Set for Download or QSAR

Found 125 hits with Last Name = 'fitch' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor (RABBIT)	BDBM50009718 (2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H23N7/c1-4-21-26-22-15(2)13-16(3)25-24(22)31(21)14-17-9-11-18(12-10-17)19-7-5-6-8-20(19)23-27-29-30-28-23/h5-13H,4,14H2,1-3H3,(H,27,28,29,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit ...				Bioorg Med Chem Lett 4: 207-212 (1994) Article DOI: 10.1016/S0960-894X(01)81148-3 BindingDB Entry DOI: 10.7270/Q2PR7VXH
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282359 (4'-(2-Ethyl-6,8-dimethyl-imidazo[1,2-b]pyridazin-3...) Show SMILES CCc1nc2c(C)cc(C)nn2c1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C30H28N4O3S/c1-4-26-27(34-29(31-26)20(2)18-21(3)32-34)19-22-14-16-23(17-15-22)25-12-8-9-13-28(25)38(36,37)33-30(35)24-10-6-5-7-11-24/h5-18H,4,19H2,1-3H3,(H,33,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity of the compound evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II re...				Bioorg Med Chem Lett 4: 219-222 (1994) Article DOI: 10.1016/S0960-894X(01)81150-1 BindingDB Entry DOI: 10.7270/Q2F76CHM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282358 (CHEMBL432734 | N-[4'-(2-Ethyl-6,8-dimethyl-imidazo...) Show SMILES CCc1nc2c(C)cc(C)nn2c1Cc1ccc(cc1)-c1ccccc1NS(=O)(=O)C(F)(F)F Show InChI InChI=1S/C24H23F3N4O2S/c1-4-20-22(31-23(28-20)15(2)13-16(3)29-31)14-17-9-11-18(12-10-17)19-7-5-6-8-21(19)30-34(32,33)24(25,26)27/h5-13,30H,4,14H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity of the compound evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II re...				Bioorg Med Chem Lett 4: 219-222 (1994) Article DOI: 10.1016/S0960-894X(01)81150-1 BindingDB Entry DOI: 10.7270/Q2F76CHM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284439 (CHEMBL15729 | [2-Allyl-6-chloro-4-(2-ethyl-5,7-dim...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1cc(Cl)c(OC(C(O)=O)c2ccccc2)c(CC=C)c1 Show InChI InChI=1S/C28H28ClN3O3/c1-5-10-21-14-19(16-32-23(6-2)31-24-17(3)13-18(4)30-27(24)32)15-22(29)25(21)35-26(28(33)34)20-11-8-7-9-12-20/h5,7-9,11-15,26H,1,6,10,16H2,2-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284453 (CHEMBL15517 | [2-Chloro-4-(2-ethyl-5,7-dimethyl-im...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(O)=O)c2ccccc2C)c(Cl)c1 Show InChI InChI=1S/C26H26ClN3O3/c1-5-22-29-23-16(3)12-17(4)28-25(23)30(22)14-18-10-11-21(20(27)13-18)33-24(26(31)32)19-9-7-6-8-15(19)2/h6-13,24H,5,14H2,1-4H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50285344 (CHEMBL40585 | [4-(7-Methyl-2-propyl-imidazo[4,5-b]...) Show SMILES CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(O)=O)c2ccccc2C)cc1 Show InChI InChI=1S/C26H27N3O3/c1-4-7-22-28-23-18(3)14-15-27-25(23)29(22)16-19-10-12-20(13-11-19)32-24(26(30)31)21-9-6-5-8-17(21)2/h5-6,8-15,24H,4,7,16H2,1-3H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for Angiotensin II receptor, type 1 binding affinity using rabbit aorta binding assay				Bioorg Med Chem Lett 5: 155-158 (1995) Article DOI: 10.1016/0960-894X(94)00476-V BindingDB Entry DOI: 10.7270/Q26H4HC9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282329 (3-(3,5-Dibromo-4-hydroxy-benzyl)-7-methyl-2-propyl...) Show SMILES CCCc1nc2c(C)cc(nc2n1Cc1cc(Br)c(O)c(Br)c1)C(=O)OC Show InChI InChI=1S/C19H19Br2N3O3/c1-4-5-15-23-16-10(2)6-14(19(26)27-3)22-18(16)24(15)9-11-7-12(20)17(25)13(21)8-11/h6-8,25H,4-5,9H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit ...				Bioorg Med Chem Lett 4: 207-212 (1994) Article DOI: 10.1016/S0960-894X(01)81148-3 BindingDB Entry DOI: 10.7270/Q2PR7VXH
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282360 (2-Ethyl-6,8-dimethyl-3-[2'-(2H-tetrazol-5-yl)-biph...) Show SMILES CCc1nc2c(C)cc(C)nn2c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H23N7/c1-4-21-22(31-24(25-21)15(2)13-16(3)28-31)14-17-9-11-18(12-10-17)19-7-5-6-8-20(19)23-26-29-30-27-23/h5-13H,4,14H2,1-3H3,(H,26,27,29,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity of the compound evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II re...				Bioorg Med Chem Lett 4: 219-222 (1994) Article DOI: 10.1016/S0960-894X(01)81150-1 BindingDB Entry DOI: 10.7270/Q2F76CHM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284454 (CHEMBL15606 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,5...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(O)=O)c2ccccc2C)cc1 Show InChI InChI=1S/C26H27N3O3/c1-5-22-28-23-17(3)14-18(4)27-25(23)29(22)15-19-10-12-20(13-11-19)32-24(26(30)31)21-9-7-6-8-16(21)2/h6-14,24H,5,15H2,1-4H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282325 (4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-yl...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1cc(I)c(O)c(I)c1 Show InChI InChI=1S/C17H17I2N3O/c1-4-14-21-15-9(2)5-10(3)20-17(15)22(14)8-11-6-12(18)16(23)13(19)7-11/h5-7,23H,4,8H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit ...				Bioorg Med Chem Lett 4: 207-212 (1994) Article DOI: 10.1016/S0960-894X(01)81148-3 BindingDB Entry DOI: 10.7270/Q2PR7VXH
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282339 (2,6-Dibromo-4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1cc(Br)c(O)c(Br)c1 Show InChI InChI=1S/C17H17Br2N3O/c1-4-14-21-15-9(2)5-10(3)20-17(15)22(14)8-11-6-12(18)16(23)13(19)7-11/h5-7,23H,4,8H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit ...				Bioorg Med Chem Lett 4: 207-212 (1994) Article DOI: 10.1016/S0960-894X(01)81148-3 BindingDB Entry DOI: 10.7270/Q2PR7VXH
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284445 ((2-Chloro-phenyl)-[4-(2-ethyl-5,7-dimethyl-imidazo...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(O)=O)c1ccccc1Cl Show InChI InChI=1S/C28H30ClN3O3/c1-5-9-20-15-19(16-32-24(6-2)31-25-17(3)14-18(4)30-27(25)32)12-13-23(20)35-26(28(33)34)21-10-7-8-11-22(21)29/h7-8,10-15,26H,5-6,9,16H2,1-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284451 (CHEMBL279103 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(O)=O)c1ccccc1OC Show InChI InChI=1S/C29H33N3O4/c1-6-10-21-16-20(17-32-25(7-2)31-26-18(3)15-19(4)30-28(26)32)13-14-23(21)36-27(29(33)34)22-11-8-9-12-24(22)35-5/h8-9,11-16,27H,6-7,10,17H2,1-5H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50282358 (CHEMBL432734 | N-[4'-(2-Ethyl-6,8-dimethyl-imidazo...) Show SMILES CCc1nc2c(C)cc(C)nn2c1Cc1ccc(cc1)-c1ccccc1NS(=O)(=O)C(F)(F)F Show InChI InChI=1S/C24H23F3N4O2S/c1-4-20-22(31-23(28-20)15(2)13-16(3)29-31)14-17-9-11-18(12-10-17)19-7-5-6-8-21(19)30-34(32,33)24(25,26)27/h5-13,30H,4,14H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity to AT2 receptor determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from AT2 receptor i...				Bioorg Med Chem Lett 4: 219-222 (1994) Article DOI: 10.1016/S0960-894X(01)81150-1 BindingDB Entry DOI: 10.7270/Q2F76CHM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284456 ((2-Chloro-phenyl)-[4-(2-ethyl-5,7-dimethyl-imidazo...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(O)=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C25H24ClN3O3/c1-4-21-28-22-15(2)13-16(3)27-24(22)29(21)14-17-9-11-18(12-10-17)32-23(25(30)31)19-7-5-6-8-20(19)26/h5-13,23H,4,14H2,1-3H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50282361 (4'-(2-Ethyl-6,8-dimethyl-imidazo[1,2-b]pyridazin-3...) Show SMILES CCc1nc2c(C)cc(C)nn2c1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C24H23N3O2/c1-4-21-22(27-23(25-21)15(2)13-16(3)26-27)14-17-9-11-18(12-10-17)19-7-5-6-8-20(19)24(28)29/h5-13H,4,14H2,1-3H3,(H,28,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity to AT2 receptor determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from AT2 receptor i...				Bioorg Med Chem Lett 4: 219-222 (1994) Article DOI: 10.1016/S0960-894X(01)81150-1 BindingDB Entry DOI: 10.7270/Q2F76CHM
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50282359 (4'-(2-Ethyl-6,8-dimethyl-imidazo[1,2-b]pyridazin-3...) Show SMILES CCc1nc2c(C)cc(C)nn2c1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C30H28N4O3S/c1-4-26-27(34-29(31-26)20(2)18-21(3)32-34)19-22-14-16-23(17-15-22)25-12-8-9-13-28(25)38(36,37)33-30(35)24-10-6-5-7-11-24/h5-18H,4,19H2,1-3H3,(H,33,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity to AT2 receptor determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from AT2 receptor i...				Bioorg Med Chem Lett 4: 219-222 (1994) Article DOI: 10.1016/S0960-894X(01)81150-1 BindingDB Entry DOI: 10.7270/Q2F76CHM
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50282360 (2-Ethyl-6,8-dimethyl-3-[2'-(2H-tetrazol-5-yl)-biph...) Show SMILES CCc1nc2c(C)cc(C)nn2c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H23N7/c1-4-21-22(31-24(25-21)15(2)13-16(3)28-31)14-17-9-11-18(12-10-17)19-7-5-6-8-20(19)23-26-29-30-27-23/h5-13H,4,14H2,1-3H3,(H,26,27,29,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity at AT2 receptor determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from rat brain memb...				Bioorg Med Chem Lett 4: 219-222 (1994) Article DOI: 10.1016/S0960-894X(01)81150-1 BindingDB Entry DOI: 10.7270/Q2F76CHM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284464 (CHEMBL15788 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,5...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(O)=O)c1ccccc1C Show InChI InChI=1S/C29H33N3O3/c1-6-10-22-16-21(17-32-25(7-2)31-26-19(4)15-20(5)30-28(26)32)13-14-24(22)35-27(29(33)34)23-12-9-8-11-18(23)3/h8-9,11-16,27H,6-7,10,17H2,1-5H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284444 (CHEMBL15689 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,5...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(O)=O)c1ccccc1 Show InChI InChI=1S/C28H31N3O3/c1-5-10-22-16-20(13-14-23(22)34-26(28(32)33)21-11-8-7-9-12-21)17-31-24(6-2)30-25-18(3)15-19(4)29-27(25)31/h7-9,11-16,26H,5-6,10,17H2,1-4H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282334 (3-(3,5-Dibromo-4-hydroxy-benzyl)-7-methyl-2-propyl...) Show SMILES CCCc1nc2c(C)cc(nc2n1Cc1cc(Br)c(O)c(Br)c1)C(O)=O Show InChI InChI=1S/C18H17Br2N3O3/c1-3-4-14-22-15-9(2)5-13(18(25)26)21-17(15)23(14)8-10-6-11(19)16(24)12(20)7-10/h5-7,24H,3-4,8H2,1-2H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit ...				Bioorg Med Chem Lett 4: 207-212 (1994) Article DOI: 10.1016/S0960-894X(01)81148-3 BindingDB Entry DOI: 10.7270/Q2PR7VXH
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284460 (CHEMBL278983 | [2-Ethyl-4-(2-ethyl-5,7-dimethyl-im...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(O)=O)c2ccccc2)c(CC)c1 Show InChI InChI=1S/C27H29N3O3/c1-5-20-15-19(12-13-22(20)33-25(27(31)32)21-10-8-7-9-11-21)16-30-23(6-2)29-24-17(3)14-18(4)28-26(24)30/h7-15,25H,5-6,16H2,1-4H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284465 (CHEMBL15847 | [2-Butyl-4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(O)=O)c1ccccc1 Show InChI InChI=1S/C29H33N3O3/c1-5-7-11-23-17-21(14-15-24(23)35-27(29(33)34)22-12-9-8-10-13-22)18-32-25(6-2)31-26-19(3)16-20(4)30-28(26)32/h8-10,12-17,27H,5-7,11,18H2,1-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284463 (CHEMBL15730 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,5...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(O)=O)c2ccccc2)c(C)c1 Show InChI InChI=1S/C26H27N3O3/c1-5-22-28-23-17(3)13-18(4)27-25(23)29(22)15-19-11-12-21(16(2)14-19)32-24(26(30)31)20-9-7-6-8-10-20/h6-14,24H,5,15H2,1-4H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284441 (CHEMBL15850 | [2-Chloro-4-(2-ethyl-5,7-dimethyl-im...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(O)=O)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C25H24ClN3O3/c1-4-21-28-22-15(2)12-16(3)27-24(22)29(21)14-17-10-11-20(19(26)13-17)32-23(25(30)31)18-8-6-5-7-9-18/h5-13,23H,4,14H2,1-3H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284455 (CHEMBL15669 | [2-Chloro-4-(2-ethyl-5,7-dimethyl-im...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1cc(Cl)c(OC(C(O)=O)c2ccccc2)c(OC)c1 Show InChI InChI=1S/C26H26ClN3O4/c1-5-21-29-22-15(2)11-16(3)28-25(22)30(21)14-17-12-19(27)24(20(13-17)33-4)34-23(26(31)32)18-9-7-6-8-10-18/h6-13,23H,5,14H2,1-4H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282326 (2,6-Dichloro-4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1cc(Cl)c(O)c(Cl)c1 Show InChI InChI=1S/C17H17Cl2N3O/c1-4-14-21-15-9(2)5-10(3)20-17(15)22(14)8-11-6-12(18)16(23)13(19)7-11/h5-7,23H,4,8H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit ...				Bioorg Med Chem Lett 4: 207-212 (1994) Article DOI: 10.1016/S0960-894X(01)81148-3 BindingDB Entry DOI: 10.7270/Q2PR7VXH
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50285349 ((2-Chloro-phenyl)-[4-(7-methyl-2-propyl-imidazo[4,...) Show SMILES CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(O)=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C25H24ClN3O3/c1-3-6-21-28-22-16(2)13-14-27-24(22)29(21)15-17-9-11-18(12-10-17)32-23(25(30)31)19-7-4-5-8-20(19)26/h4-5,7-14,23H,3,6,15H2,1-2H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for Angiotensin II receptor, type 1 binding affinity using rabbit aorta binding assay				Bioorg Med Chem Lett 5: 155-158 (1995) Article DOI: 10.1016/0960-894X(94)00476-V BindingDB Entry DOI: 10.7270/Q26H4HC9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50285356 ((2-Ethoxy-phenyl)-[4-(7-methyl-2-propyl-imidazo[4,...) Show SMILES CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(O)=O)c2ccccc2OCC)cc1 Show InChI InChI=1S/C27H29N3O4/c1-4-8-23-29-24-18(3)15-16-28-26(24)30(23)17-19-11-13-20(14-12-19)34-25(27(31)32)21-9-6-7-10-22(21)33-5-2/h6-7,9-16,25H,4-5,8,17H2,1-3H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for Angiotensin II receptor, type 1 binding affinity using rabbit aorta binding assay				Bioorg Med Chem Lett 5: 155-158 (1995) Article DOI: 10.1016/0960-894X(94)00476-V BindingDB Entry DOI: 10.7270/Q26H4HC9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284462 (CHEMBL278234 | [2-Allyl-4-(2-ethyl-5,7-dimethyl-im...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(O)=O)c2ccccc2)c(CC=C)c1 Show InChI InChI=1S/C28H29N3O3/c1-5-10-22-16-20(13-14-23(22)34-26(28(32)33)21-11-8-7-9-12-21)17-31-24(6-2)30-25-18(3)15-19(4)29-27(25)31/h5,7-9,11-16,26H,1,6,10,17H2,2-4H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50285345 ((4-Chloro-2-cyclohexyl-phenoxy)-(4-chloro-phenyl)-...) Show SMILES OC(=O)C(Oc1ccc(Cl)cc1C1CCCCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H20Cl2O3/c21-15-8-6-14(7-9-15)19(20(23)24)25-18-11-10-16(22)12-17(18)13-4-2-1-3-5-13/h6-13,19H,1-5H2,(H,23,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for Angiotensin II receptor, type 1 binding affinity using rabbit aorta binding assay				Bioorg Med Chem Lett 5: 155-158 (1995) Article DOI: 10.1016/0960-894X(94)00476-V BindingDB Entry DOI: 10.7270/Q26H4HC9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50285353 ((2,6-Dichloro-phenyl)-[4-(7-methyl-2-propyl-imidaz...) Show SMILES CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(O)=O)c2c(Cl)cccc2Cl)cc1 Show InChI InChI=1S/C25H23Cl2N3O3/c1-3-5-20-29-22-15(2)12-13-28-24(22)30(20)14-16-8-10-17(11-9-16)33-23(25(31)32)21-18(26)6-4-7-19(21)27/h4,6-13,23H,3,5,14H2,1-2H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for Angiotensin II receptor, type 1 binding affinity using rabbit aorta binding assay				Bioorg Med Chem Lett 5: 155-158 (1995) Article DOI: 10.1016/0960-894X(94)00476-V BindingDB Entry DOI: 10.7270/Q26H4HC9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284448 (CHEMBL280290 | [2,6-Dichloro-4-(2-ethyl-5,7-dimeth...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1cc(Cl)c(OC(C(O)=O)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C25H23Cl2N3O3/c1-4-20-29-21-14(2)10-15(3)28-24(21)30(20)13-16-11-18(26)23(19(27)12-16)33-22(25(31)32)17-8-6-5-7-9-17/h5-12,22H,4,13H2,1-3H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50285349 ((2-Chloro-phenyl)-[4-(7-methyl-2-propyl-imidazo[4,...) Show SMILES CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(O)=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C25H24ClN3O3/c1-3-6-21-28-22-16(2)13-14-27-24(22)29(21)15-17-9-11-18(12-10-17)32-23(25(30)31)19-7-4-5-8-20(19)26/h4-5,7-14,23H,3,6,15H2,1-2H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for Angiotensin II receptor, type 2 binding affinity using rabbit aorta binding assay				Bioorg Med Chem Lett 5: 155-158 (1995) Article DOI: 10.1016/0960-894X(94)00476-V BindingDB Entry DOI: 10.7270/Q26H4HC9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282336 (4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-yl...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1cc(I)c(O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C17H17IN4O3/c1-4-14-20-15-9(2)5-10(3)19-17(15)21(14)8-11-6-12(18)16(23)13(7-11)22(24)25/h5-7,23H,4,8H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit ...				Bioorg Med Chem Lett 4: 207-212 (1994) Article DOI: 10.1016/S0960-894X(01)81148-3 BindingDB Entry DOI: 10.7270/Q2PR7VXH
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50117909 (CHEMBL278176 | N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(=O)NS(=O)(=O)c1ccc(cc1)C(C)C)c1ccc2OCOc2c1 Show InChI InChI=1S/C38H42N4O6S/c1-7-9-28-19-26(21-42-34(8-2)40-35-24(5)18-25(6)39-37(35)42)10-16-31(28)48-36(29-13-17-32-33(20-29)47-22-46-32)38(43)41-49(44,45)30-14-11-27(12-15-30)23(3)4/h10-20,23,36H,7-9,21-22H2,1-6H3,(H,41,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human endothelin A (ETA) receptor expressed in CHO cells				Bioorg Med Chem Lett 5: 1155-1158 (1995) Article DOI: 10.1016/0960-894X(95)00186-W BindingDB Entry DOI: 10.7270/Q2DF6R5F
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282341 (1,1,2,2,3,3,4,4,4-Nonafluoro-butane-1-sulfonic aci...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(Oc2ccccc2NS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1 Show InChI InChI=1S/C27H23F9N4O3S/c1-4-21-38-22-15(2)13-16(3)37-23(22)40(21)14-17-9-11-18(12-10-17)43-20-8-6-5-7-19(20)39-44(41,42)27(35,36)25(30,31)24(28,29)26(32,33)34/h5-13,39H,4,14H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit ...				Bioorg Med Chem Lett 4: 207-212 (1994) Article DOI: 10.1016/S0960-894X(01)81148-3 BindingDB Entry DOI: 10.7270/Q2PR7VXH
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284457 (CHEMBL15671 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,5...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(O)=O)c2ccccc2)cc1 Show InChI InChI=1S/C25H25N3O3/c1-4-21-27-22-16(2)14-17(3)26-24(22)28(21)15-18-10-12-20(13-11-18)31-23(25(29)30)19-8-6-5-7-9-19/h5-14,23H,4,15H2,1-3H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284442 (CHEMBL15882 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,5...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(O)=O)c2ccccc2)c(c1)C(C)C Show InChI InChI=1S/C28H31N3O3/c1-6-24-30-25-18(4)14-19(5)29-27(25)31(24)16-20-12-13-23(22(15-20)17(2)3)34-26(28(32)33)21-10-8-7-9-11-21/h7-15,17,26H,6,16H2,1-5H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282338 (2-[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1Oc1ccccc1C(O)=O Show InChI InChI=1S/C30H35N3O3/c1-6-11-22-16-21(18-33-26(8-3)32-27-19(4)15-20(5)31-29(27)33)17-23(12-7-2)28(22)36-25-14-10-9-13-24(25)30(34)35/h9-10,13-17H,6-8,11-12,18H2,1-5H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit ...				Bioorg Med Chem Lett 4: 207-212 (1994) Article DOI: 10.1016/S0960-894X(01)81148-3 BindingDB Entry DOI: 10.7270/Q2PR7VXH
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50285346 (CHEMBL288222 | [4-(7-Methyl-2-propyl-imidazo[4,5-b...) Show SMILES CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(O)=O)c2cccc3ccccc23)cc1 Show InChI InChI=1S/C29H27N3O3/c1-3-7-25-31-26-19(2)16-17-30-28(26)32(25)18-20-12-14-22(15-13-20)35-27(29(33)34)24-11-6-9-21-8-4-5-10-23(21)24/h4-6,8-17,27H,3,7,18H2,1-2H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for Angiotensin II receptor, type 1 binding affinity using rabbit aorta binding assay				Bioorg Med Chem Lett 5: 155-158 (1995) Article DOI: 10.1016/0960-894X(94)00476-V BindingDB Entry DOI: 10.7270/Q26H4HC9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50285358 ((2-Methoxy-phenyl)-[4-(7-methyl-2-propyl-imidazo[4...) Show SMILES CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(O)=O)c2ccccc2OC)cc1 Show InChI InChI=1S/C26H27N3O4/c1-4-7-22-28-23-17(2)14-15-27-25(23)29(22)16-18-10-12-19(13-11-18)33-24(26(30)31)20-8-5-6-9-21(20)32-3/h5-6,8-15,24H,4,7,16H2,1-3H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for Angiotensin II receptor, type 1 binding affinity using rabbit aorta binding assay				Bioorg Med Chem Lett 5: 155-158 (1995) Article DOI: 10.1016/0960-894X(94)00476-V BindingDB Entry DOI: 10.7270/Q26H4HC9
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50284470 (Benzo[1,3]dioxol-5-yl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C32H37N3O5/c1-6-9-22-14-21(17-35-27(8-3)34-28-19(4)13-20(5)33-31(28)35)15-23(10-7-2)29(22)40-30(32(36)37)24-11-12-25-26(16-24)39-18-38-25/h11-16,30H,6-10,17-18H2,1-5H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human endothelin A (ETA) receptor expressed in CHO cells				Bioorg Med Chem Lett 5: 1155-1158 (1995) Article DOI: 10.1016/0960-894X(95)00186-W BindingDB Entry DOI: 10.7270/Q2DF6R5F
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284459 (CHEMBL274260 | [4-(7-Methyl-2-propyl-imidazo[4,5-b...) Show SMILES CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(O)=O)c2ccccc2)cc1 Show InChI InChI=1S/C25H25N3O3/c1-3-7-21-27-22-17(2)14-15-26-24(22)28(21)16-18-10-12-20(13-11-18)31-23(25(29)30)19-8-5-4-6-9-19/h4-6,8-15,23H,3,7,16H2,1-2H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for Angiotensin II receptor, type 1 binding affinity using rabbit aorta binding assay				Bioorg Med Chem Lett 5: 155-158 (1995) Article DOI: 10.1016/0960-894X(94)00476-V BindingDB Entry DOI: 10.7270/Q26H4HC9
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50284444 (CHEMBL15689 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,5...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(O)=O)c1ccccc1 Show InChI InChI=1S/C28H31N3O3/c1-5-10-22-16-20(13-14-23(22)34-26(28(32)33)21-11-8-7-9-12-21)17-31-24(6-2)30-25-18(3)15-19(4)29-27(25)31/h7-9,11-16,26H,5-6,10,17H2,1-4H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rat midbrain membrane (AT2 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50284450 (CHEMBL15774 | [2-tert-Butyl-4-(2-ethyl-5,7-dimethy...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(O)=O)c2ccccc2)c(c1)C(C)(C)C Show InChI InChI=1S/C29H33N3O3/c1-7-24-31-25-18(2)15-19(3)30-27(25)32(24)17-20-13-14-23(22(16-20)29(4,5)6)35-26(28(33)34)21-11-9-8-10-12-21/h8-16,26H,7,17H2,1-6H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282342 (CHEMBL63280 | N-{2-[4-(2-Ethyl-5,7-dimethyl-imidaz...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(Oc2ccccc2NS(=O)(=O)C(F)(F)F)cc1 Show InChI InChI=1S/C24H23F3N4O3S/c1-4-21-29-22-15(2)13-16(3)28-23(22)31(21)14-17-9-11-18(12-10-17)34-20-8-6-5-7-19(20)30-35(32,33)24(25,26)27/h5-13,30H,4,14H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit ...				Bioorg Med Chem Lett 4: 207-212 (1994) Article DOI: 10.1016/S0960-894X(01)81148-3 BindingDB Entry DOI: 10.7270/Q2PR7VXH
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50285351 (CHEMBL39124 | [4-(7-Methyl-2-propyl-imidazo[4,5-b]...) Show SMILES CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(O)=O)c2ccccc2[N+]([O-])=O)cc1 Show InChI InChI=1S/C25H24N4O5/c1-3-6-21-27-22-16(2)13-14-26-24(22)28(21)15-17-9-11-18(12-10-17)34-23(25(30)31)19-7-4-5-8-20(19)29(32)33/h4-5,7-14,23H,3,6,15H2,1-2H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for Angiotensin II receptor, type 1 binding affinity using rabbit aorta binding assay				Bioorg Med Chem Lett 5: 155-158 (1995) Article DOI: 10.1016/0960-894X(94)00476-V BindingDB Entry DOI: 10.7270/Q26H4HC9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50285355 ((3-Chloro-phenyl)-[4-(7-methyl-2-propyl-imidazo[4,...) Show SMILES CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(O)=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C25H24ClN3O3/c1-3-5-21-28-22-16(2)12-13-27-24(22)29(21)15-17-8-10-20(11-9-17)32-23(25(30)31)18-6-4-7-19(26)14-18/h4,6-14,23H,3,5,15H2,1-2H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for Angiotensin II receptor, type 1 binding affinity using rabbit aorta binding assay				Bioorg Med Chem Lett 5: 155-158 (1995) Article DOI: 10.1016/0960-894X(94)00476-V BindingDB Entry DOI: 10.7270/Q26H4HC9
					More data for this Ligand-Target Pair
Endothelin receptor type B (Homo sapiens (Human))	BDBM50117909 (CHEMBL278176 | N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(=O)NS(=O)(=O)c1ccc(cc1)C(C)C)c1ccc2OCOc2c1 Show InChI InChI=1S/C38H42N4O6S/c1-7-9-28-19-26(21-42-34(8-2)40-35-24(5)18-25(6)39-37(35)42)10-16-31(28)48-36(29-13-17-32-33(20-29)47-22-46-32)38(43)41-49(44,45)30-14-11-27(12-15-30)23(3)4/h10-20,23,36H,7-9,21-22H2,1-6H3,(H,41,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human endothelin B (ETB) receptor expressed in CHO cells				Bioorg Med Chem Lett 5: 1155-1158 (1995) Article DOI: 10.1016/0960-894X(95)00186-W BindingDB Entry DOI: 10.7270/Q2DF6R5F
					More data for this Ligand-Target Pair

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