| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Coagulation factor X |
|---|
| Ligand | BDBM50041220 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_69652 |
|---|
| Ki | 570000±n/a nM |
|---|
| Citation |  Quan, ML; Pruitt, JR; Ellis, CD; Liauw, AY; Galemmo, RA; Stouten, PF; Wityak, J; Knabb, RM; Thoolen, MJ; Wong, PC; Wexler, RR Bisbenzamidine isoxazoline derivatives as factor Xa inhibitors Bioorg Med Chem Lett7:2813-2818 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Coagulation factor X |
|---|
| Name: | Coagulation factor X |
|---|
| Synonyms: | Coagulation factor X | F10 | FA10_BOVIN | Factor Xa (fXa) |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 54498.45 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_1364435 |
|---|
| Residue: | 492 |
|---|
| Sequence: | MAGLLHLVLLSTALGGLLRPAGSVFLPRDQAHRVLQRARRANSFLEEVKQGNLERECLEE
ACSLEEAREVFEDAEQTDEFWSKYKDGDQCEGHPCLNQGHCKDGIGDYTCTCAEGFEGKN
CEFSTREICSLDNGGCDQFCREERSEVRCSCAHGYVLGDDSKSCVSTERFPCGKFTQGRS
RRWAIHTSEDALDASELEHYDPADLSPTESSLDLLGLNRTEPSAGEDGSQVVRIVGGRDC
AEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTEQEEGNEM
AHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEATLMTQKTGIV
SGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPEDACQGDSGG
PHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMKARAGAAGSRGHSEA
PATWTVPPPLPL
|
|
|
|---|
| BDBM50041220 |
|---|
| n/a |
|---|
| Name | BDBM50041220 |
|---|
| Synonyms: | 1,2-bis(5-amidinobenzofuran-2-yl)ethane | 2-(2-{5-[(E)-amino(imino)methyl]-1-benzofuran-2-yl}ethyl)-1-benzofuran-5-carboximidamide | 2-(2-{5-[(Z)-amino(imino)methyl]-1-benzofuran-2-yl}ethyl)-1-benzofuran-5-carboximidamide | 2-{2-[5-amino(imino)methylbenzo[b]furan-2-yl]ethyl}benzo[b]furan-5-yl-iminomethanamine | CHEMBL279962 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H18N4O2 |
|---|
| Mol. Mass. | 346.3825 |
|---|
| SMILES | NC(=N)c1ccc2oc(CCc3cc4cc(ccc4o3)C(N)=N)cc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
