| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C5a anaphylatoxin chemotactic receptor 1 |
|---|
| Ligand | BDBM50291452 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_41450 (CHEMBL652972) |
|---|
| IC50 | 800±n/a nM |
|---|
| Citation |  Astles, PC; Brown, TJ; Cox, P; Halley, F; Lockey, PM; McCarthy, C; McLay, IM; Majid, TN; Morley, AD; Porter, B; Ratcliffe, AJ; Walsh, RJ New non peptidic C5a receptor antagonists Bioorg Med Chem Lett7:907-912 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C5a anaphylatoxin chemotactic receptor 1 |
|---|
| Name: | C5a anaphylatoxin chemotactic receptor 1 |
|---|
| Synonyms: | C5AR | C5AR1 | C5AR1_HUMAN | C5R1 | C5a anaphylatoxin chemotactic receptor | C5a anaphylatoxin chemotactic receptor (C5aR) | C5a-R | CD_antigen=CD88 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39347.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21730 |
|---|
| Residue: | 350 |
|---|
| Sequence: | MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVW
VTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNM
YASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREE
YFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKT
LKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIY
VVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
|
|
|
|---|
| BDBM50291452 |
|---|
| n/a |
|---|
| Name | BDBM50291452 |
|---|
| Synonyms: | CHEMBL368161 | N-Methyl-N'-(6-phenethyloxy-biphenyl-3-yl)-guanidine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H23N3O |
|---|
| Mol. Mass. | 345.4375 |
|---|
| SMILES | CNC(N)=Nc1ccc(OCCc2ccccc2)c(c1)-c1ccccc1 |w:4.4| |
|---|
| Structure | 
|
|---|
Search and Browse
