| Reaction Details |
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 | Report a problem with these data |
| Target | C5a anaphylatoxin chemotactic receptor 1 |
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| Ligand | BDBM50291465 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_41460 |
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| IC50 | 1000±n/a nM |
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| Citation |  Astles, PC; Brown, TJ; Cox, P; Halley, F; Lockey, PM; McCarthy, C; McLay, IM; Majid, TN; Morley, AD; Porter, B; Ratcliffe, AJ; Walsh, RJ New non peptidic C5a receptor antagonists Bioorg Med Chem Lett7:907-912 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C5a anaphylatoxin chemotactic receptor 1 |
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| Name: | C5a anaphylatoxin chemotactic receptor 1 |
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| Synonyms: | C5AR | C5AR1 | C5AR1_HUMAN | C5R1 | C5a anaphylatoxin chemotactic receptor | C5a anaphylatoxin chemotactic receptor (C5aR) | C5a-R | CD_antigen=CD88 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39347.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21730 |
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| Residue: | 350 |
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| Sequence: | MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVW
VTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNM
YASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREE
YFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKT
LKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIY
VVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
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| BDBM50291465 |
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| n/a |
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| Name | BDBM50291465 |
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| Synonyms: | CHEMBL173442 | N-[6-(2-Cyclohexyl-ethoxy)-biphenyl-3-yl]-N'-methyl-guanidine |
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| Type | Small organic molecule |
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| Emp. Form. | C22H29N3O |
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| Mol. Mass. | 351.4852 |
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| SMILES | CNC(N)=Nc1ccc(OCCC2CCCCC2)c(c1)-c1ccccc1 |w:4.4| |
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| Structure | 
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