| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP1 subtype |
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| Ligand | BDBM50414549 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_581538 (CHEMBL1059841) |
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| Ki | >25118.86±n/a nM |
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| Citation |  Hilfiker, MA; Wang, N; Hou, X; Du, Z; Pullen, MA; Nord, M; Nagilla, R; Fries, HE; Wu, CW; Sulpizio, AC; Jaworski, JP; Morrow, D; Edwards, RM; Jin, J Discovery of novel aminothiadiazole amides as selective EP(3) receptor antagonists. Bioorg Med Chem Lett19:4292-5 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP1 subtype |
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| Name: | Prostaglandin E2 receptor EP1 subtype |
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| Synonyms: | PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41834.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34995 |
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| Residue: | 402 |
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| Sequence: | MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF
GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE
LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR
PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV
GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR
QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
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| BDBM50414549 |
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| n/a |
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| Name | BDBM50414549 |
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| Synonyms: | CHEMBL563480 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16Cl2N4O2S |
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| Mol. Mass. | 435.327 |
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| SMILES | CCN1CCOc2ccc(cc12)C(=O)Nc1nnc(s1)-c1c(Cl)cccc1Cl |
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| Structure | 
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