| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2C |
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| Ligand | BDBM50302151 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_598874 (CHEMBL1044706) |
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| EC50 | 25±n/a nM |
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| Citation |  Allerton, CM; Andrews, MD; Blagg, J; Ellis, D; Evrard, E; Green, MP; Liu, KK; McMurray, G; Ralph, M; Sanderson, V; Ward, R; Watson, L Design and synthesis of pyridazinone-based 5-HT(2C) agonists. Bioorg Med Chem Lett19:5791-5 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2C |
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| Name: | 5-hydroxytryptamine receptor 2C |
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| Synonyms: | 5-HT-1C | 5-HT-2C | 5-HT1C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 51836.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P28335 |
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| Residue: | 458 |
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| Sequence: | MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSI
VIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW
PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWA
ISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYV
LRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTM
QAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVC
SGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTN
EPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
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| BDBM50302151 |
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| n/a |
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| Name | BDBM50302151 |
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| Synonyms: | (S)-2-(1-(2-chlorophenoxy)propan-2-yl)-6-(piperazin-1-yl)pyridazin-3(2H)-one | CHEMBL572252 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21ClN4O2 |
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| Mol. Mass. | 348.827 |
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| SMILES | C[C@@H](COc1ccccc1Cl)n1nc(ccc1=O)N1CCNCC1 |r| |
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| Structure | 
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