| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Death-associated protein kinase 3 |
|---|
| Ligand | BDBM50314669 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_625624 (CHEMBL1112575) |
|---|
| IC50 | 359.60±n/a nM |
|---|
| Citation |  Okamoto, M; Takayama, K; Shimizu, T; Muroya, A; Furuya, T Structure-activity relationship of novel DAPK inhibitors identified by structure-based virtual screening. Bioorg Med Chem18:2728-34 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Death-associated protein kinase 3 |
|---|
| Name: | Death-associated protein kinase 3 |
|---|
| Synonyms: | DAP kinase 3 | DAP-like kinase | DAPK3 | DAPK3_HUMAN | ZIP-kinase | ZIPK |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 52537.07 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_586564 |
|---|
| Residue: | 454 |
|---|
| Sequence: | MSTFRQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREE
IEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFL
KQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGT
PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEY
FSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVRGEDSGRKPERRRLKTT
RLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAEEGLRELQRSRRLCHEDVEALAAIY
EEKEAWYREESDSLGQDLRRLRQELLKTEALKRQAQEEAKGALLGTSGLKRRFSRLENRY
EALAKQVASEMRFVQDLVRALEQEKLQGVECGLR
|
|
|
|---|
| BDBM50314669 |
|---|
| n/a |
|---|
| Name | BDBM50314669 |
|---|
| Synonyms: | 2-(3-chlorophenyl)-4-(pyridin-3-ylmethylene)oxazol-5(4H)-one | CHEMBL1091765 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H9ClN2O2 |
|---|
| Mol. Mass. | 284.697 |
|---|
| SMILES | Clc1cccc(c1)C1=N\C(=C/c2cccnc2)C(=O)O1 |t:8| |
|---|
| Structure | 
|
|---|
Search and Browse
